GALNT2

  • Official Full Name

    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)

  • Overview

    This gene encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation in a cell is regulated by a repertoire of GalNAc-transferases.

  • Synonyms

    GALNT2;UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2);polypeptide N-acetylgalactosaminyltransferase 2;GalNAc T2;GalNAc-T2;GALT2_HUMAN;GaNTase 2;Polypeptide GalNAc transferase 2;Polypeptide N acetylgalactosaminyltransferase 2 soluble form;Polypeptide N-acetylgalactosaminyltransferase 2 soluble form;pp GaNTase 2;pp-GaNTase 2;Protein UDP acetylgalactosaminyltransferase 2;Protein-UDP acetylgalactosaminyltransferase 2;UDP GalNAc transferase 2;UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2;UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2;UDP-GalNAc transferase 2

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Mouse
  • Zebrafish
  • Rhizobia
  • E.coli
  • Mammalian Cell
  • Human Cell
  • Wheat Germ
  • HEK293
  • HEK293T
  • P. pastoris
  • His
  • Fc
  • Non
  • Myc&DDK
  • His&Fc&Avi
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
GALNT2-13136H Recombinant Human GALNT2, His-tagged E.coli Human His 222-571a.a.
GALNT2-1807R Recombinant Rhesus monkey GALNT2 Protein, His-tagged Mammalian Cell Rhesus macaque His
GALNT2-229H Recombinant Human GALNT2, His tagged Human Cell Human Fc 52-571 a.a.
GALNT2-27303TH Recombinant Human GALNT2 Wheat Germ Human Non 99 amino acids
GALNT2-585H Recombinant Human GALNT2 Mammalian Cell Human His
GALNT2-6185M Recombinant Mouse GALNT2 Protein Mammalian Cell Mouse His
GALNT2-6862Z Recombinant Zebrafish GALNT2 Mammalian Cell Zebrafish His
GALNT2-907HCL Recombinant Human GALNT2 cell lysate Human Cell Human Non
GALNT2-1252H Recombinant Human GALNT2 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
GALNT2-1265H Recombinant Human GALNT2 protein, His-tagged HEK293 Human His Lys52-Gln571
GALNT2-1478H Recombinant Human GALNT2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
GALNT2-1628R Recombinant Rhesus Macaque GALNT2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
GALNT2-1628R-B Recombinant Rhesus Macaque GALNT2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GALNT2-3005H Recombinant Human GALNT2 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
GALNT2-3005H-B Recombinant Human GALNT2 Protein Pre-coupled Magnetic Beads HEK293 Human
GALNT2-3450M Recombinant Mouse GALNT2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
GALNT2-3450M-B Recombinant Mouse GALNT2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Galnt2-366M Recombinant Mouse Galnt2 Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK
GALNT2-4698H Recombinant Human GALNT2 Protein P. pastoris Human Non Full L.
GALNT2-4699H Recombinant Human GALNT2 Protein, GST-tagged Wheat Germ Human GST
GALNT2-4700R Recombinant Rhizobia GALNT2 Protein E.coli Rhizobia Non Full L.

    Involved Pathway

    GALNT2 involved in several pathways and played different roles in them. We selected most pathways GALNT2 participated on our site, such as Mucin type O-Glycan biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALNT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways PAPSS2A,ALOX5A,DAO1,NT5C3B,TM7SF2,CMPK2,AKR1B8,DAO.2,ST6GALNAC4,PHYKPL
    Mucin type O-Glycan biosynthesis GALNTL5,GALNT4,GALNTL4,GALNTL6,B3GNT6,GALNT11,ST3GAL2,GALNT10,GALNT7,B4GALT5

    Protein Function

    GALNT2 has several biochemical functions, for example, carbohydrate binding,manganese ion binding,polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GALNT2 itself. We selected most functions GALNT2 had, and list some proteins which have the same functions with GALNT2. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding LMAN2,CLEC2D,CLEC6A,FCNA,LGALSLB,CLEC3B,NOMO2,FCN1,ATRN,G6PDX
    polypeptide N-acetylgalactosaminyltransferase activity GALNTL2,GALNT4,GALNTL6,GALNT9,GALNT13,GALNT7,GALNT3,GALNTL1,GALNT11,WBSCR17
    protein binding PRKX,UBXN1,GABPB1,KLHL35,AP5Z1,PAX3,CYCS,ZNF329,CCDC6,HYI
    manganese ion binding HMGCL,PAPOLA,PPM1NB,PPM1B,PPM1BA,WRN,ATP2C1,PPEF2,SOD2,GALNT3

    Interacting Protein

    GALNT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALNT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALNT2.

    CCDC155;NOD2;AP4M1;Shoc2;Itgb1;PTPN1;Rab5c;Rad54l;REEP5;Papss1;MMGT1;Tor1aip1;Hspa14;Mis12;AP4S1;Uso1

    Resources

    References

    • Ho, WL; Chou, CH; et al. GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma. ONCOTARGET 5:12247-12259(2014).
    • Cole, CB; Nikpay, M; et al. Adiposity significantly modifies genetic risk for dyslipidemia. JOURNAL OF LIPID RESEARCH 55:2416-2422(2014).

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All GALNT2 Products

    Required fields are marked with *

    My Review for All GALNT2 Products

    Required fields are marked with *