GALNT13

  • Product List
  • Overview
  • Review / Q&A

  • Official Full Name

    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)

  • Overview

    The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.

  • Synonyms

    GALNT13;UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13);polypeptide N-acetylgalactosaminyltransferase 13;GalNAc T13;KIAA1918;UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 13;GalNAc transferase 13;N acetylgalactosaminyltransferase 13;Polypeptide GalNAc transferase 13;pp GaNTase 13;Protein UDP acetylgalactosaminyltransferase 13;UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13;UDP N acetyl alpha D galactosamine:polypeptide;pp-GaNTase 13;protein-UDP acetylgalactosaminyltransferase 13;UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13;GalNAc-T13;H_NH0187G20.1;WUGSC:H_NH0187G20.1

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • HEK293
  • Mammalian Cells
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • DDK
  • Myc
  • Non
  • Avi
  • Fc
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
GALNT13-622H Active Recombinant Human GALNT13 protein, His-tagged HEK293 Human His 29-556 a.a.
GALNT13-2467R Recombinant Rat GALNT13 Protein Mammalian Cells Rat His
GALNT13-623H Recombinant Human GALNT13 protein, MYC/DDK-tagged HEK293 Human DDK&Myc
GALNT13-6038HCL Recombinant Human GALNT13 293 Cell Lysate HEK293 Human Non
GALNT13-2123R Recombinant Rat GALNT13 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GALNT13-2123R-B Recombinant Rat GALNT13 Protein Pre-coupled Magnetic Beads HEK293 Rat
Galnt13-3142M Recombinant Mouse Galnt13 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
GALNT13-4693H Recombinant Human GALNT13 Protein, GST-tagged Wheat Germ Human GST
GALNT13-5197HF Recombinant Full Length Human GALNT13 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 556 amino acids
GALNT13-6166H Recombinant Human GALNT13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc

Involved Pathway

GALNT13 involved in several pathways and played different roles in them. We selected most pathways GALNT13 participated on our site, such as Metabolic pathways,Metabolism of proteins,Mucin type O-Glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALNT13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mucin core 1 and core 2 O-glycosylation GALNTL2,GALNT5,GCNT3,GALNT6
O-linked glycosylation ADAMTS1,SSPO,ADAMTS18,MUC12,B3GNT8,THSD7A,MUC15,MUC21,C8orf84,GALNTL2
Post-translational protein modification MAGT1,SSPO,ARSI,NSMCE4A,ADAMTS13,ADAMTS20,SENP1,ALG10B,NSMCE1,ARSD
Mucin type O-Glycan biosynthesis GALNT1,ST3GAL1,GALNT6,GALNT11,GALNT7,GALNTL4,GALNT9,GALNT14,GALNTL6,GALNT18
Metabolism of proteins EEF1A2,ARSH,EIF5A2,GALNT5,CCDC59,MBOAT4,TMED10,DOHH,ODAM,PREB
Metabolic pathways DPAGT1,UPB1,PIP5KL1,COX4I1,AOX2P,SQLE,ATP6V0E1,PIGF,PLD2,NDUFV3
O-linked glycosylation of mucins ST6GALNAC2,GCNT3,B3GNT6,GALNTL5,MUC1,GALNTL2,MUC5AC,MUC4,KCNA6,MUC21

Protein Function

GALNT13 has several biochemical functions, for example, carbohydrate binding,metal ion binding,polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GALNT13 itself. We selected most functions GALNT13 had, and list some proteins which have the same functions with GALNT13. You can find most of the proteins on our site.

Function Related Protein
carbohydrate binding LGALSLB,LGALS14,CLEC5A,NCAN,CANX,HIST2H3C2,CD302,GALNT7,KRT1,GANAB
polypeptide N-acetylgalactosaminyltransferase activity GALNT3,C1GALT1C1,GALNT1,GALNT14,GALNTL6,GALNTL4,GALNT12,GALNT9,GALNT5,GALNT10
metal ion binding SDHDB,MAT2AB,HAGHL,FURIN,CYP4A10,PPARAB,CYP2C70,MYBPC3,PRSS37,ZNF561

Interacting Protein

GALNT13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALNT13 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALNT13.

Resources

References

  • Dominguez, F; Moreno-Moya, JM; et al. Embryonic miRNA Profiles of Normal and Ectopic Pregnancies. PLOS ONE 9:-(2014).
  • Hussain, MRM; Nasir, J; et al. Clinically Significant Missense Variants in Human GALNT3, GALNT8, GALNT12, and GALNT13 Genes: Intriguing In Silico Findings. JOURNAL OF CELLULAR BIOCHEMISTRY 115:313-327(2014).

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