GALNT13
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Official Full Name
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13) -
Overview
The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue. -
Synonyms
GALNT13;UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13);polypeptide N-acetylgalactosaminyltransferase 13;GalNAc T13;KIAA1918;UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 13;GalNAc transferase 13;N acetylgalactosaminyltransferase 13;Polypeptide GalNAc transferase 13;pp GaNTase 13;Protein UDP acetylgalactosaminyltransferase 13;UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 13;UDP N acetyl alpha D galactosamine:polypeptide;pp-GaNTase 13;protein-UDP acetylgalactosaminyltransferase 13;UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13;GalNAc-T13;H_NH0187G20.1;WUGSC:H_NH0187G20.1
Recombinant Proteins
- Human
- Rat
- Mouse
- HEK293
- Mammalian Cell
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GALNT13-622H |
Active Recombinant Human GALNT13 protein, His-tagged
|
HEK293 | Human | His | 29-556 a.a. |
|
| GALNT13-2467R | Recombinant Rat GALNT13 Protein | Mammalian Cell | Rat | His |
|
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| GALNT13-623H | Recombinant Human GALNT13 protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
|
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| GALNT13-6038HCL | Recombinant Human GALNT13 293 Cell Lysate | HEK293 | Human | Non |
|
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| GALNT13-2123R | Recombinant Rat GALNT13 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
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| GALNT13-2123R-B | Recombinant Rat GALNT13 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Galnt13-3142M | Recombinant Mouse Galnt13 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| GALNT13-4693H | Recombinant Human GALNT13 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GALNT13-5197HF | Recombinant Full Length Human GALNT13 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 556 amino acids |
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| GALNT13-6166H | Recombinant Human GALNT13 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
Involved Pathway
GALNT13 involved in several pathways and played different roles in them. We selected most pathways GALNT13 participated on our site, such as Metabolic pathways,Metabolism of proteins,Mucin type O-Glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALNT13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | LASS5,DEGS1,SUCLG2,ARSB,HMBSB,CYP2R1,FUK,ST8SIA1,DMGDH,AGXT2L2 |
| Mucin type O-Glycan biosynthesis | GALNT14,GALNT18A,B4GALT5,C1GALT1C1,GALNTL4,GALNT1,GALNT5,WBSCR17,GALNT9,GALNTL2 |
| Post-translational protein modification | MUC13,CNIH2,ADAMTS5,EIF5A,PPP6R3,MAN1A2,ADAMTS8,ADAMTS13,NSMCE1,PIGK |
| O-linked glycosylation of mucins | GALNT5,KCNA6,MUC15,B3GNT6,MUC20,GCNT3,GALNTL5,GALNT6,MUC4,MUCL1 |
| O-linked glycosylation | ADAMTS1,SSPO,B3GNT6,B3GALTL,GALNT6,ADAMTSL4,ST6GALNAC2,MUC1,KCNA6,THSD1 |
| mucin core 1 and core 2 O-glycosylation | GALNTL2,GALNT5,GALNT6,GCNT3 |
| Metabolism of proteins | CGB5,APEH,ST6GALNAC2,CCT7,ATPBD4,UBA2,EEF1A2,PROCA,B3GNT3,INHA |
Protein Function
GALNT13 has several biochemical functions, for example, carbohydrate binding,metal ion binding,polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GALNT13 itself. We selected most functions GALNT13 had, and list some proteins which have the same functions with GALNT13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | CLEC1B,ACAN,LGALS7B,UAP1,ITLN1,KLRC4-KLRK1,GALNTL6,CD209B,OLR1,LGALS9C |
| polypeptide N-acetylgalactosaminyltransferase activity | GALNT11,GALNTL4,GALNT4,GALNT12,GALNT7,GALNT3,GALNT10,GALNTL2,GALNT5,GALNTL1 |
| metal ion binding | ZNF784,PRKCQ,ZNF652,MSS51,ACVR1,TIMP4,CASZ1,ZFP503,VPS18,ADCY6 |
Interacting Protein
GALNT13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALNT13 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALNT13.
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References
- Dominguez, F; Moreno-Moya, JM; et al. Embryonic miRNA Profiles of Normal and Ectopic Pregnancies. PLOS ONE 9:-(2014).
- Hussain, MRM; Nasir, J; et al. Clinically Significant Missense Variants in Human GALNT3, GALNT8, GALNT12, and GALNT13 Genes: Intriguing In Silico Findings. JOURNAL OF CELLULAR BIOCHEMISTRY 115:313-327(2014).
