GAL3ST1
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Official Full Name
galactose-3-O-sulfotransferase 1 -
Overview
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3-phosphoadenylylsulfate + a galactosylceramide to adenosine 3,5-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. -
Synonyms
GAL3ST1;galactose-3-O-sulfotransferase 1;galactosylceramide sulfotransferase;cerebroside (3 phosphoadenylylsulfate:galactosylceramide 3) sulfotransferase;CST;3 phosphoadenosine 5 phosphosulfate:GalCer sulfotransferase;3 phosphoadenylylsulfate:galactosylceramide 3 sulfotransferase;Cerebroside sulfotransferase;Galactose 3 O sulfotransferase 1;GalCer sulfotransferase;3-phosphoadenosine-5-phosphosulfate:GalCer sulfotransferase;3-phosphoadenylylsulfate:galactosylceramide 3-sulfotransferase;cerebroside (3-phosphoadenylylsulfate:galactosylceramide 3) sulfotransferase
Recombinant Proteins
- Rhesus macaque
- Human
- Rat
- Mammalian Cell
- HEK293
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&GST
- His&T7
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GAL3ST1-1801R | Recombinant Rhesus monkey GAL3ST1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| GAL3ST1-6046HCL | Recombinant Human GAL3ST1 293 Cell Lysate | HEK293 | Human | Non |
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| GAL3ST1-1615H | Recombinant Human GAL3ST1 protein, His & GST-tagged | E.coli | Human | His&GST | Leu57~Phe196 |
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| Gal3st1-1616R | Recombinant Rat Gal3st1 protein, His & T7-tagged | E.coli | Rat | His&T7 | Arg215~Trp423 |
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| GAL3ST1-1622R | Recombinant Rhesus Macaque GAL3ST1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| GAL3ST1-1622R-B | Recombinant Rhesus Macaque GAL3ST1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| GAL3ST1-3307H | Recombinant Human GAL3ST1 Protein (Leu57-Phe196), N-GST tagged | E.coli | Human | GST | Leu57-Phe196 |
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| GAL3ST1-4672H | Recombinant Human GAL3ST1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GAL3ST1-5219HF | Recombinant Full Length Human GAL3ST1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 423 amino acids |
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Involved Pathway
GAL3ST1 involved in several pathways and played different roles in them. We selected most pathways GAL3ST1 participated on our site, such as Ether lipid metabolism,Sphingolipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GAL3ST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ether lipid metabolism | PLA2G1B,PLA2G2E,PPAP2C,CHPT1,TMEM86B,PLA2G4A,PAFAH1B1B,PLA2G4B,PAFAH1B1,CEPT1 |
| Sphingolipid metabolism | GALCA,GBA2,ACER3,SERINC1,CERS4,ARSH,NEU3.5,SMPD5,ARSJ,B4GALT6 |
| Metabolic pathways | PAFAH1B1B,ACSL4A,GALNT7,PRODH2,B4GALT7,SYNJ1,ADH7,PCCA,PGLS,FBP1A |
Protein Function
GAL3ST1 has several biochemical functions, for example, galactosylceramide sulfotransferase activity,sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GAL3ST1 itself. We selected most functions GAL3ST1 had, and list some proteins which have the same functions with GAL3ST1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| galactosylceramide sulfotransferase activity | GAL3ST4,GAL3ST3,GAL3ST1A |
| sulfotransferase activity | CHST12A,SULT1ST5,CHST10,SULT3ST4,SULT3ST3,HS3ST3B1B,SULT1ST8,CHST1,SULT5A1,SULT1A2 |
Interacting Protein
GAL3ST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GAL3ST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GAL3ST1.
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References
- Hering, DM; Olenski, K; et al. Genome-Wide Association Study for Sperm Concentration in Holstein-Friesian Bulls. REPRODUCTION IN DOMESTIC ANIMALS 49:1008-1014(2014).
- Goetstouwers, T; Van Poucke, M; et al. Variation in 12 porcine genes involved in the carbohydrate moiety assembly of glycosphingolipids does not account for differential binding of F4 Escherichia coli and their fimbriae. BMC GENETICS 15:-(2014).
