GABPB1

  • Official Full Name

    GA binding protein transcription factor, beta subunit 1

  • Overview

    This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex;with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in;activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a;similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding;distinct isoforms have been identified for this gene.

  • Synonyms

    GABPB1;GA binding protein transcription factor, beta subunit 1;GA binding protein transcription factor, beta subunit 2 , GABPB2;GA-binding protein subunit beta-1;E4TF1 47;GABPB;BABPB2;E4TF1;E4TF1-47;E4TF1-53;E4TF1B;GA binding protein transcription factor, beta subunit 2;GABP subunit beta-1;GABP subunit beta-2;GABP1_HUMAN;GABPB-1;GABPB-2;GABPB2;NRF2B1;NRF2B2;Nuclear respiratory factor 2;Transcription factor E4TF1-47;Transcription factor E4TF1-53

Recombinant Proteins

  • Chicken
  • Rhesus macaque
  • Human
  • Zebrafish
  • Mammalian Cells
  • Wheat Germ
  • E.coli
  • Sf9 Cells
  • HEK293
  • In Vitro Cell Free System
  • His
  • Non
  • GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
GABPB1-1258C Recombinant Chicken GABPB1 Mammalian Cells Chicken His
GABPB1-1791R Recombinant Rhesus monkey GABPB1 Protein, His-tagged Mammalian Cells Rhesus macaque His
GABPB1-27461TH Recombinant Human GABPB1 Wheat Germ Human Non 87 amino acids
GABPB1-4729Z Recombinant Zebrafish GABPB1 Mammalian Cells Zebrafish His
GABPB1-50H Recombinant Human GABPB1 protein, His-tagged E.coli Human His 363aa(including fusion tag)
GABPB1-5260H Recombinant Full Length Human GABPB1 Protein (1-395), GST-tagged Sf9 Cells Human GST Full L. 1-395 (Full Length)
GABPB1-6068HCL Recombinant Human GABPB1 293 Cell Lysate HEK293 Human Non
GABPB1-001H Recombinant Human GABPB1 Protein, His-tagged E.coli Human His 1-395
GABPB1-05H Recombinant Human GABPB1 Protein, N-His-tagged E.coli Human His Full L.
GABPB1-06H Recombinant Human GABPB1 Protein, N-His-tagged E.coli Human His Full L.
GABPB1-1612R Recombinant Rhesus Macaque GABPB1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
GABPB1-1612R-B Recombinant Rhesus Macaque GABPB1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GABPB1-4633H Recombinant Human GABPB1 Protein, GST-tagged Wheat Germ Human GST
GABPB1-5180HF Recombinant Full Length Human GABPB1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 395 amino acids

    Involved Pathway

    GABPB1 involved in several pathways and played different roles in them. We selected most pathways GABPB1 participated on our site, such as Mitochondrial biogenesis,Myometrial Relaxation and Contraction Pathways,Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABPB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transcriptional activation of mitochondrial biogenesis PPRC1,TFB1M,MTERF,C10orf2,POLRMT,GABPA,POLG2
    Myometrial Relaxation and Contraction Pathways CNN2,RGS10,IGFBP2,RGS19,RAMP1,GABPA,RGS4,IGFBP4,CRH,ACTA1
    Mitochondrial biogenesis POLRMT,GABPA,TFB2M,TFB1M,MTERF,POLG2,PPRC1,C10orf2,ESRRA,PPARGC1B
    Organelle biogenesis and maintenance MRPS31,PKD1,TCTN3,MKKS,BBS1,MRPL52,MTFMT,MRPL28,POLG2,OST4

    Protein Function

    GABPB1 has several biochemical functions, for example, protein binding,protein heterodimerization activity,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GABPB1 itself. We selected most functions GABPB1 had, and list some proteins which have the same functions with GABPB1. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, sequence-specific DNA binding ZNF12,POU2F1A,NFIC,TEFB,MEOX1,ZNF334,TAF1B,NEUROD1,DMRT2A,WT1B
    protein binding TFDP1,TCEB2,OCA2,GOLGA8G,SNX2,FAM9A,IRF2,DOK6,PTPRJ,C6orf108
    transcription regulatory region DNA binding ZFP639,XRCC6,KCNA3,Ar,TFAP4,TP53,TRP53,SP1,IKZF2,RBBP5
    protein heterodimerization activity VEGFB,UBA2,UGT1A4,TPD52,IKZF1,DLG4B,AHR,PDZD7,SDCBP,HIST2H4A

    Interacting Protein

    GABPB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABPB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABPB1.

    LMO1;TRAF2;TDRD7;MAGEB18;Adgrb2;SNRPB2

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