FUK
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Official Full Name
fucokinase -
Overview
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. -
Synonyms
FUK;fucokinase;L-fucose kinase;FLJ39408;L fucose kinase;FUK_HUMAN;OTTHUMP00000082728;OTTHUMP00000082729;1110046B12Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FUK-13033H | Recombinant Human FUK, His-tagged | E.coli | Human | His | 695-1084a.a. | |
| FUK-676HCL | Recombinant Human FUK cell lysate | Human | Non |
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| FUK-2660H | Recombinant Human FUK Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| FUK-4547H | Recombinant Human FUK Protein, GST-tagged | Wheat Germ | Human | GST |
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| FUK-5136HF | Recombinant Full Length Human FUK Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 1084 amino acids |
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Involved Pathway
FUK involved in several pathways and played different roles in them. We selected most pathways FUK participated on our site, such as Amino sugar and nucleotide sugar metabolism,Fructose and mannose metabolism,GDP-L-fucose biosynthesis II (from L-fucose), which may be useful for your reference. Also, other proteins which involved in the same pathway with FUK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | POLR2L,MTM1,DGKZ,AMDHD1,PLA2G10,INPP5K,BCKDHA,ENO3,NDUFV3,GPAT2 |
| Fructose and mannose metabolism | PFKMB,HK2,AKR1B8,AKR1B1L,ALDOAA,Akr1b3,AKR1B10,PFKFB3,DHRS13L1,PFKFB2 |
| Amino sugar and nucleotide sugar metabolism | PMM1,UGDH,GALE,PGM2,RENBP,HK1,GPI,UGP2,GNPDA2,HKDC1 |
Protein Function
FUK has several biochemical functions, for example, ATP binding,fucokinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FUK itself. We selected most functions FUK had, and list some proteins which have the same functions with FUK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | STK10,NLRP4,CHD4A,SRPK2,ATP2C1,ADCY6,NLRP14,C9orf96,TRIP13,ERCC6L2 |
Interacting Protein
FUK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUK here. Most of them are supplied by our site. Hope this information will be useful for your research of FUK.
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References
- Zou, YN; Kim, D; et al. Application of LDH-Release Assay to Cellular-Level Evaluation of the Toxic Potential of Harmful Algal Species. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77:345-352(2013).
- Mendez-Vigo, B; Martinez-Zapater, JM; et al. The Flowering Repressor SVP Underlies a Novel Arabidopsis thaliana QTL Interacting with the Genetic Background. PLOS GENETICS 9:-(2013).
