FOXQ1

  • Official Full Name

    forkhead box Q1
  • Overview

    FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called;the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation,;tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 (PubMed 11747606)).
  • Synonyms

    FOXQ1;forkhead box Q1;forkhead box protein Q1;HFH1;FOX Q1;FOXQ 1;FOXQ1_HUMAN;Hepatocyte nuclear factor 3 forkhead;Hepatocyte nuclear factor 3 forkhead homolog 1;HFH 1;HFH-1;HNF 3/forkhead like protein 1;HNF-3/forkhead-like protein 1;HNF3/forkhead like protein 1;MGC77469;Q1;Winged helix / forkhead transcription factor;Winged helix/forkhead transcription factor;zgc:77469

Recombinant Proteins

  • Rat
  • Mouse
  • Human
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Wheat Germ
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
  • GST

    Involved Pathway

    FOXQ1 involved in several pathways and played different roles in them. We selected most pathways FOXQ1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXQ1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    FOXQ1 has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXQ1 itself. We selected most functions FOXQ1 had, and list some proteins which have the same functions with FOXQ1. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II transcription factor activity, sequence-specific DNA binding OVOL2,MEF2A,MKX,ATF4,ETV5B,SOX14,ZNF202,SOX5,TFAP2B,SIX1A
    sequence-specific DNA binding WT1,EMX3,NKX3.3,NKX6-1,LEF1,OTX1A,MAFK,NKX1.2LA,ATF4B1,DLX3

    Interacting Protein

    FOXQ1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXQ1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXQ1.

    Dlg4

    Resources

    References

    • Meng, FY; Speyer, CL; et al. PDGFR alpha and beta Play Critical Roles in Mediating Foxq1-Driven Breast Cancer Stemness and Chemoresistance. CANCER RESEARCH 75:584-593(2015).
    • Zhang, J; Yang, Y; et al. Double-Negative Feedback Loop Between MicroRNA-422a and Forkhead Box (FOX)G1/Q1/E1 Regulates Hepatocellular Carcinoma Tumor Growth and Metastasis. HEPATOLOGY 61:561-573(2015).

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