FOXK2

  • Official Full Name

    forkhead box K2

  • Overview

    The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements.

  • Synonyms

    FOXK2;forkhead box K2;ILF, ILF1, interleukin enhancer binding factor 1;forkhead box protein K2;Cellular transcription factor ILF 1;Cellular transcription factor ILF-1;Cellular transcription factor ILF1;FOX K1;FOX K2;FOXK 1;FOXK 2;FOXK1;FOXK2_HUMAN;Interleukin enhancer binding factor 1;Interleukin enhancer-binding factor 1;ILF;ILF1;ILF-1
Cat.# Product name Source (Host) Species Tag Protein Length Price
FOXK2-29031TH Recombinant Human FOXK2 Wheat Germ Human Non 100 amino acids
FOXK2-5998M Recombinant Mouse FOXK2 Protein Mammalian Cell Mouse His
FOXK2-7825Z Recombinant Zebrafish FOXK2 Mammalian Cell Zebrafish His
FOXK2-11H Recombinant Human FOXK2 protein, His-tagged C-His Human Arg321-Pro650
FOXK2-3329M Recombinant Mouse FOXK2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
FOXK2-3329M-B Recombinant Mouse FOXK2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    FOXK2 involved in several pathways and played different roles in them. We selected most pathways FOXK2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    FOXK2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,magnesium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXK2 itself. We selected most functions FOXK2 had, and list some proteins which have the same functions with FOXK2. You can find most of the proteins on our site.

    Function Related Protein
    sequence-specific DNA binding FOXO3B,TFCP2,FOXC2,POU3F1,Trl,MEF2A,USF1,WHSC1,FOXO1B,CEBPG
    magnesium ion binding PPM1AB,ITPK1A,ADPRH,S100P,NIM1,TSSK6,ZNF143B,HPRT1,ENO4,GEM
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GLIS2,FOSL1,ZSCAN21,JUNB,MAFA,TCF4,NEUROD6,NR4A3,CARF,RUNX2
    protein binding HSPE1,FRMPD2,DRD1A,GLYR1,CTNNBL1,SULT1B1,ACO1,SULT1A1,LRRFIP2,DUSP5
    transcription factor activity, sequence-specific DNA binding POU3F4,UBN2,ZNF583,HSF2,SMAD5,CREM,SIM1B,ATF6B,NFIC,ZNF256
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GLI2,POU4F3,HOXD13,NKX6-2,E2F4,CRX,RBPJ,ETS2,TP73,PAX8

    Interacting Protein

    FOXK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXK2.

    IRF2;AMOT;BAP1;lutB;hutU;N;SAP30;CTR9;P;Kat8;MAP1LC3B;MAP1LC3A

    Resources

    Research Area

    Muscle Stem Cell Markers
    Myogenesis Markers
    Myogenic Precursor Markers

    References

    • Fujii, Y; Nakamura, M; et al. FOXK2 transcription factor is a novel G/T-mismatch DNA binding protein. JOURNAL OF BIOCHEMISTRY 147:705-709(2010).

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