FLVCR2
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Official Full Name
feline leukemia virus subgroup C cellular receptor family, member 2 -
Overview
This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described. -
Synonyms
FLVCR2;feline leukemia virus subgroup C cellular receptor family, member 2;C14orf58, chromosome 14 open reading frame 58 , feline leukemia virus subgroup C cellular receptor 2;feline leukemia virus subgroup C receptor-related protein 2;FLJ20371;MFS
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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FLVCR2-1984H | Recombinant Human FLVCR2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK | ||
FLVCR2-2436H | Recombinant Human FLVCR2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK | ||
FLVCR2-301269H | Recombinant Human FLVCR2 protein, GST-tagged | E.coli | Human | GST | Phe476-Leu526 | |
Flvcr2-3047M | Recombinant Mouse Flvcr2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK | ||
FLVCR2-4382H | Recombinant Human FLVCR2 Protein | Wheat Germ | Human | Non | ||
FLVCR2-4971HF | Recombinant Full Length Human FLVCR2 Protein | In Vitro Cell Free System | Human | Full L. 192 amino acids |
Involved Pathway
FLVCR2 involved in several pathways and played different roles in them. We selected most pathways FLVCR2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FLVCR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
FLVCR2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FLVCR2 itself. We selected most functions FLVCR2 had, and list some proteins which have the same functions with FLVCR2. You can find most of the proteins on our site.
Function | Related Protein |
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Interacting Protein
FLVCR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FLVCR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FLVCR2.
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References
- Chiabrando, D; Vinchi, F; et al. Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes. FRONTIERS IN PHARMACOLOGY 5:-(2014).
- Soster, EL; Tucker, M; et al. Hydranencephaly in a Newborn with a FLVCR2 Mutation and Prenatal Exposure to Cocaine. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY 103:45-50(2015).