FKBP8
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Official Full Name
FK506 binding protein 8, 38kDa -
Overview
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. [provided by RefSeq, Jul 2008] -
Synonyms
FKBP8;FK506 binding protein 8, 38kDa;FKBP38;FKBPr38;peptidyl-prolyl cis-trans isomerase FKBP8;FKBP-8;FKBP-38;hFKBP38;rotamase;38 kDa FKBP;PPIase FKBP8;38 kDa FK506-binding protein;FK506-binding protein 8 (38kD)
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Rhesus macaque
- Rat
- Chicken
- Mus musculus
- Mammalian Cell
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli expression system
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
FKBP8 involved in several pathways and played different roles in them. We selected most pathways FKBP8 participated on our site, such as Role of Calcineurin-dependent NFAT signaling in lymphocytes,Senescence and Autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with FKBP8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Role of Calcineurin-dependent NFAT signaling in lymphocytes | RCAN1,CHP,RCAN2 |
| Senescence and Autophagy | IFI16,RB1CC1,ING1,MAP1LC3C,IGFBP7,AMBRA1,COL10A1,SLC39A3,SLC39A1,SLC39A2 |
Protein Function
FKBP8 has several biochemical functions, for example, FK506 binding,identical protein binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FKBP8 itself. We selected most functions FKBP8 had, and list some proteins which have the same functions with FKBP8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptidyl-prolyl cis-trans isomerase activity | FKBP3,TTC9B,FKBP1B,FKBP1AA,FKBP14,FKBP10B,PPIAB,CWC27,PPIAA,PPIFA |
| FK506 binding | TTC9C,TTC9B,FKBP3,NFATC1,FKBP10,FKBP2,FKBP7,FKBP9,FKBP1AB,FKBP4 |
| protein binding | OLA1,SMAD5,ANXA10,UBA52,CDK5R1,UTP14A,PPFIA4,EAF2,CD2AP,ITGA2 |
| identical protein binding | MYOM1,EPOR,SLC22A1,PRDX1,CDC42,SAFB2,APPL1,BCL2L1,B2M,TRA@ |
| metal ion binding | AMDHD2,ZFP579,YY1B,PRLR,MMP13A,PAPD4,ZDHHC16B,EXT1B,LACTB2,ZFP36 |
Interacting Protein
FKBP8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FKBP8 here. Most of them are supplied by our site. Hope this information will be useful for your research of FKBP8.
NS5A;q9wmx2-pro_0000037551
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