FHL5
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Official Full Name
four and a half LIM domains 5 -
Overview
The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. -
Synonyms
FHL5;four and a half LIM domains 5;four and a half LIM domains protein 5;ACT;dJ393D12.2;FLJ33049;Activator of cAMP responsive element modulator (CREM) in testis;Activator of CREM in testis;FHL5 protein;FHL-5;1700027G07Rik;LIM protein ACT;OTTHUMP00000016879;OTTHUMP00000016880;activator of cAMP-responsive element modulator in testis;activator of cAMP-responsive element modulator (CREM) in t;RP3-393D12.2
Recombinant Proteins
- Zebrafish
- Rat
- Chicken
- Cynomolgus
- Human
- Mammalian Cell
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&GST
- Non
- His&Fc&Avi
- GST
Involved Pathway
FHL5 involved in several pathways and played different roles in them. We selected most pathways FHL5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FHL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FHL5 has several biochemical functions, for example, protein binding,transcription coactivator activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FHL5 itself. We selected most functions FHL5 had, and list some proteins which have the same functions with FHL5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription coactivator activity | SMARCC2,PRDM16,CCNE1,MED21,ATF6,BRDT,CDK7,TRIP4,GMEB1,GTF2A2 |
| protein binding | BAG1,EXOC8,PRMT3,PITX1,CD81,RNF139,PARVG,RIOK3,FAM162A,RNF19B |
| zinc ion binding | EWSR1B,GATA4,TRIM33,ZZZ3,PRDM4,BIRC5,USP45,ZFYVE1,MBD1,CPA1 |
Interacting Protein
FHL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FHL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of FHL5.
Hoxa1;DNAL4;COIL;FAM214B;yvsH
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References
