FHL1

  • Official Full Name

    four and a half LIM domains 1

  • Overview

    This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.

  • Synonyms

    FHL1;four and a half LIM domains 1;four and a half LIM domains protein 1;bA535K18.1;FHL1B;FLH1A;KYO T;LIM protein SLIMMER;MGC111107;SLIM1;XMPMA;FHL 1;FHL 1B;FHL-1;FHL1 protein;FHL1_HUMAN;FHL1A;Four and a half Lin11 Isl 1 and Mec 3 domains 1;RAM14-1;RBP associated molecule 14-1;Skeletal muscle LIM protein 1;Skeletal muscle LIM-protein 1;SLIM 1;SLIM;SLIM-1;SLIMMER;OTTHUMP00000024097;OTTHUMP00000024098;OTTHUMP00000024099;OTTHUMP00000024100;OTTHUMP00000024101;OTTHUMP00000024102;OTTHUMP00000024103;OTTHUMP00000024104;OTTHUMP00000024106;OTTHUMP00000024107;skeleta;KYOT

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • HEK293
  • Wheat Germ
  • Human cells
  • Mammalian cells
  • HEK293T
  • Mamanlian cells
  • GST
  • Myc&DDK
  • Non
  • His
  • Flag
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
FHL1-12888H Recombinant Human FHL1, GST-tagged E.coli Human GST 1-280a.a.
FHL1-128H Recombinant Human FHL1, MYC/DDK-tagged HEK293 Human Myc&DDK
FHL1-28103TH Recombinant Human FHL1 protein, GST-tagged Wheat Germ Human GST 1-280 a.a.
FHL1-28893TH Recombinant Human FHL1 Wheat Germ Human Non 98 amino acids
FHL1-6225HCL Recombinant Human FHL1 293 Cell Lysate HEK293 Human Non
FHL1-1142H Recombinant Human FHL1 protein, His-tagged E.coli Human His 2-323aa
FHL1-151H Recombinant Human FHL1 Protein, His-tagged Human cells Human His
FHL1-1688HFL Recombinant Full Length Human FHL1 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
Fhl1-3011M Recombinant Mouse Fhl1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
FHL1-4604HFL Recombinant Full Length Human FHL1, Flag-tagged Mamanlian cells Human Flag Full L.
FHL1-914H Recombinant Human FHL1 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
FHL1-914H-B Recombinant Human FHL1 Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    FHL1 involved in several pathways and played different roles in them. We selected most pathways FHL1 participated on our site, such as Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FHL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Jak-STAT signaling pathway PIK3R5,GFAP,HRAS,IL13RA1,IL11RA,IFNA16,IL12BA,PIAS2,PIK3R2,IL29

    Protein Function

    FHL1 has several biochemical functions, for example, ion channel binding,molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FHL1 itself. We selected most functions FHL1 had, and list some proteins which have the same functions with FHL1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TAG-260,HBQ1,EPHA2,ZC3H10,DPEP3,THBS2,ECE2,CDC23,PCDH17,PRKRIR
    ion channel binding PPP1R9B,FYN,AP2M1,KCNH5,KCNB2,PACS1A,PKP2,SCN3B,RIMS1,FKBP1A
    molecular_function DNAJB13,RPRMB,NACAD,SCRN1,CCDC63,SEC24A,TMEM238,ACTR3B,M1AP,HAUS4
    zinc ion binding TRIML1,CA4,TCEA2,C6AST1,NUP153,RNF17,BIRC5,USP16,KDM4C,AGBL1

    Interacting Protein

    FHL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FHL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FHL1.

    NRIP1;AKAP12;PRNP;SRPK1;ESR1;EPB41;MCC;HLA-B;IKBKE;PRKAB1;DEAF1;EED;ENO1;ZNF16

    Resources

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