FCRL4
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Official Full Name
Fc receptor-like 4 -
Overview
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. -
Synonyms
FCRL4;Fc receptor-like 4;Fc receptor-like protein 4;CD307d;FCRH4;IGFP2;IRTA1;Fc receptor homolog 4;Fc receptor like 4;Fc receptor like protein 4;FcR like protein 4;IFGP family protein 2;Immune receptor translocation associated protein 1;Immunoglobulin superfamily receptor translocation associated 1;Immunoglobulin superfamily receptor translocation associated gene 1;hIFGP2;fcR-like protein 4;immunoglobulin superfamily Fc receptor, gp42;immune receptor translocation-associated protein 1
Recombinant Proteins
- Human
- Rhesus macaque
- HEK293
- Human Cells
- E.coli
- Yeast
- Mamanlian cells
- Myc&DDK
- Fc
- hIgG4
- His
- Non
- Flag
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FCRL4-12H | Recombinant Human FCRL4 protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| FCRL4-1718R | Recombinant Rhesus Monkey FCRL4 Protein, hIgG1-tagged | HEK293 | Rhesus macaque | Fc | 20-395 a.a. |
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| FCRL4-1719R | Recombinant Rhesus Monkey FCRL4 Protein, hIgG4-tagged | HEK293 | Rhesus macaque | hIgG4 | 20-395 a.a. |
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| FCRL4-920H | Recombinant Human FCRL4 protein, His-tagged | HEK293 | Human | His | 20-387aa |
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| FCRL4-6274HCL | Recombinant Human FCRL4 293 Cell Lysate | HEK293 | Human | Non |
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| FCRL4-151H | Recombinant Human FCRL4 Protein, DYKDDDDK-tagged | Human Cells | Human | Flag |
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| FCRL4-1798H | Recombinant Human FCRL4 Protein (20-387 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 20-387 aa |
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| FCRL4-1843H | Recombinant Human FCRL4 Protein (20-387 aa), His-tagged | Yeast | Human | His | 20-387 aa |
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| FCRL4-2643HFL | Recombinant Full Length Human FCRL4 protein, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
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Involved Pathway
FCRL4 involved in several pathways and played different roles in them. We selected most pathways FCRL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FCRL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FCRL4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCRL4 itself. We selected most functions FCRL4 had, and list some proteins which have the same functions with FCRL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PRC1,HMOX1,AHNAK2,GBP5,CARHSP1,FZD8,HAX1,EIF2S3,CLOCK,AATF |
Interacting Protein
FCRL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCRL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCRL4.
TFF1;TFF2
Resources
Research Area
Fc ReceptorsITIM/ITAM Immunoreceptors and Related Molecules
B Cell Receptor-Associated Proteins
Related Services
Related Products
References
- Amu, S; Lavy-Shahaf, G; et al. Frequency and phenotype of B cell subpopulations in young and aged HIV-1 infected patients receiving ART. RETROVIROLOGY 11:-(2014).
- Ben Mkaddem, S; Christou, I; et al. IgA, IgA Receptors, and Their Anti-inflammatory Properties. FC RECEPTORS 382:221-235(2014).
