FCRL3
-
Official Full Name
Fc receptor-like 3 -
Overview
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like;glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine;activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in;regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune;thyroid disease, and systemic lupus erythematosus. -
Synonyms
FCRL3;Fc receptor-like 3;Fc receptor-like protein 3;CD307c;FCRH3;IFGP3;IRTA3;SPAP2;SPAP2a;SPAP2b;SPAP2c;SPAP2d;SPAP2e;hIFGP3;fcR-like protein 3;Fc receptor homolog 3;IFGP family protein 3;SH2 domain-containing phosphatase anchor protein 2
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian cells
- HEK293
- Wheat Germ
- His
- Non
- Fc
- hIgG4
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FCRL3-12830H | Recombinant Human FCRL3, His-tagged | E.coli | Human | His | 1-302a.a. | |
| FCRL3-795H |
Active Recombinant Human FCRL3 Protein, His-tagged
|
Mammalian cells | Human | His | Arg14-Arg569 |
|
| FCRL3-1715R | Recombinant Rhesus Monkey FCRL3 Protein | HEK293 | Rhesus macaque | Non | 24-590 a.a. |
|
| FCRL3-1716R | Recombinant Rhesus Monkey FCRL3 Protein, hIgG1-tagged | HEK293 | Rhesus macaque | Fc | 24-590 a.a. |
|
| FCRL3-1717R | Recombinant Rhesus Monkey FCRL3 Protein, hIgG4-tagged | HEK293 | Rhesus macaque | hIgG4 | 24-590 a.a. |
|
| FCRL3-4009H | Recombinant Human FCRL3 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| FCRL3-2939H | Recombinant Human FCRL3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
|
| FCRL3-2939H-B | Recombinant Human FCRL3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
||
| FCRL3-5633H | Recombinant Human FCRL3 protein, His-tagged | E.coli | Human | His | 18-573a.a. |
|
Involved Pathway
FCRL3 involved in several pathways and played different roles in them. We selected most pathways FCRL3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FCRL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FCRL3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FCRL3 itself. We selected most functions FCRL3 had, and list some proteins which have the same functions with FCRL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
FCRL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCRL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCRL3.
Resources
Research Area
Fc ReceptorsITIM/ITAM Immunoreceptors and Related Molecules
B Cell Receptor-Associated Proteins
Related Services
Related Products
References
- Marino, M; Latrofa, F; et al. Role of genetic and non-genetic factors in the etiology of Graves' disease. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 38:283-294(2015).
- Piotrowski, P; Lianeri, M; et al. The FCRL3-169T > C polymorphism might be associated with some autoantibody presence in patients with SLE in a Polish population. MODERN RHEUMATOLOGY 24:296-299(2014).
