FBXL8

  • Official Full Name

    F-box and leucine-rich repeat protein 8

  • Overview

    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein.

  • Synonyms

    FBXL8;F-box and leucine-rich repeat protein 8;F-box/LRR-repeat protein 8;Fbl8;F box and leucine rich repeat protein 8;F box protein FBL8;F box/LRR repeat protein 8;FBL 8;Fbxl 8;F-box protein FBL8

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293T
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
FBXL8-12782H Recombinant Human FBXL8, His-tagged E.coli Human His 1-374a.a.
FBXL8-3537Z Recombinant Zebrafish FBXL8 Mammalian Cell Zebrafish His
FBXL8-3912H Recombinant Human FBXL8 Protein, GST-tagged Wheat Germ Human GST
FBXL8-5058C Recombinant Chicken FBXL8 Mammalian Cell Chicken His
FBXL8-5059C Recombinant Chicken FBXL8 Mammalian Cell Chicken His
FBXL8-602HCL Recombinant Human FBXL8 cell lysate Human Non
Fbxl8-2963M Recombinant Mouse Fbxl8 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
FBXL8-5006HF Recombinant Full Length Human FBXL8 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 374 amino acids

    Involved Pathway

    FBXL8 involved in several pathways and played different roles in them. We selected most pathways FBXL8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXL8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    FBXL8 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXL8 itself. We selected most functions FBXL8 had, and list some proteins which have the same functions with FBXL8. You can find most of the proteins on our site.

    Function Related Protein
    protein binding RBM12B,BCR,ARL6IP1,PATL1,SPTAN1,ZNF426,USP54,LAPTM4B,FCER2,TKT

    Interacting Protein

    FBXL8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXL8 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXL8.

    SKP1;HSP90AB1;ORC4;Chmp6

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