FBLN2

  • Official Full Name

    fibulin 2
  • Overview

    This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms

    FBLN2;fibulin 2;fibulin-2;FBLN2_HUMAN;FIBL-2;OTTHUMP00000216670;OTTHUMP00000216671;OTTHUMP00000216672

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • HA
  • His&T7
  • Non
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
FBLN2-159H Recombinant Human FBLN2 Protein, His-tagged E.coli Human His Ile858~Ser1069
FBLN2-01H Active Recombinant Human FBLN2 protein, HA-tagged HEK293 Human HA 28-1184 a.a.
FBLN2-198H Recombinant Human FBLN2 protein, T7/His-tagged E.coli Human His&T7 28-1184 a.a.
FBLN2-28902TH Recombinant Human FBLN2 Wheat Germ Human Non 109 amino acids
FBLN2-3874H Recombinant Human FBLN2 Protein, GST-tagged Wheat Germ Human GST
Fbln2-7896M Recombinant Mouse Fbln2 protein, His-tagged E.coli Mouse His Val896~Glu1106
Fbln2-7897R Recombinant Rat Fbln2 protein, His-tagged E.coli Rat His Asp1013~Pro1221
FBLN2-2600H Recombinant Human FBLN2 Protein (Asp858-Leu1184), N-His tagged E.coli Human His Asp858-Leu1184
FBLN2-4882HF Recombinant Full Length Human FBLN2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 28-1184 amino acids

    Involved Pathway

    FBLN2 involved in several pathways and played different roles in them. We selected most pathways FBLN2 participated on our site, such as Elastic fibre formation,Extracellular matrix organization,Molecules associated with elastic fibres, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBLN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Extracellular matrix organization LTBP3,ADAMTS1,PCOLCE2B,COL28A1D,COL16A1,CEACAM8,CEACAM1,ADAMTS18,MATN4,P3H2
    Molecules associated with elastic fibres LTBP4,BMP10,LTBP3,MFAP3,MFAP1,EFEMP2,EFEMP1,MFAP2,FBLN1,LTBP2
    Elastic fibre formation LTBP4,LOXL3,FURINA,MFAP1B,EFEMP1,FBN1,MFAP3,LTBP3,MFAP4,LOXL4

    Protein Function

    FBLN2 has several biochemical functions, for example, calcium ion binding,extracellular matrix binding,extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by FBLN2 itself. We selected most functions FBLN2 had, and list some proteins which have the same functions with FBLN2. You can find most of the proteins on our site.

    Function Related Protein
    extracellular matrix structural constituent ACAN,FBLN1,COL8A2,MATN1,TINAGL1,KAL1,COL5A1,ELNA,COL4A5,COL24A1
    calcium ion binding SULF2,Amy1,RAB11FIP4,NID2,MAN1A2,PVALB6,CABP1B,MYL9B,NCS1B,PVALB4
    extracellular matrix binding SID4,TGFBI,ITGA2B,CYR61,ITGB3,CD248,ITGAV,VTN,BGN,SPOCK2

    Interacting Protein

    FBLN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBLN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBLN2.

    ATN1;ZYX;htrA;mnmG;TFAP2C;q9wmx2-pro_0000037541;q9wmx2-pro_0000037546;q9wmx2-pro_0000037548

    Resources

    Research Area

    Other ECM Glycoproteins

    References

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