FBLIM1

  • Official Full Name

    filamin binding LIM protein 1

  • Overview

    This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

  • Synonyms

    FBLIM1;filamin binding LIM protein 1;filamin-binding LIM protein 1;CAL;FBLP 1;migfilin;FBLP1;Mitogen inducible 2 interacting protein;OTTHUMP00000003118;OTTHUMP00000003119;OTTHUMP00000003120;2410043F08Rik;CSX associated LIM;DKFZp434G171;FBLI1_HUMAN;FBLIM 1;FBLP-1;Gt10;MGC105665;MIG2 interacting protein;MIG2-interacting protein;Mitogen-inducible 2-interacting protein;OTTMUSP00000011062;OTTMUSP00000011063;RP11-169K16.5;RP23-291H3.1;CSX-associated LIM;OTTHUMP00000221650;filamin-binding LIM protein-1;mitogen-inducible 2 interacting protein;mitogen-inducible 2-intera

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • E.coli
  • Wheat Germ
  • Mammalian Cell
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
FBLIM1-12763H Recombinant Human FBLIM1, GST-tagged E.coli Human GST 1-373a.a.
FBLIM1-3870H Recombinant Human FBLIM1 Protein, GST-tagged Wheat Germ Human GST
FBLIM1-4671Z Recombinant Zebrafish FBLIM1 Mammalian Cell Zebrafish His
FBLIM1-5699M Recombinant Mouse FBLIM1 Protein Mammalian Cell Mouse His
FBLIM1-7602H Recombinant Human FBLIM1, His-tagged E.coli Human Non 1-373aa
FBLIM1-6318HCL Recombinant Human FBLIM1 293 Cell Lysate HEK293 Human Non
FBLIM1-2538H Recombinant Human FBLIM1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Fblim1-2958M Recombinant Mouse Fblim1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
FBLIM1-3131M Recombinant Mouse FBLIM1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
FBLIM1-3131M-B Recombinant Mouse FBLIM1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
FBLIM1-4878HF Recombinant Full Length Human FBLIM1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 276 amino acids

    Involved Pathway

    FBLIM1 involved in several pathways and played different roles in them. We selected most pathways FBLIM1 participated on our site, such as Cell junction organization,Cell-Cell communication,Cell-extracellular matrix interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBLIM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell-Cell communication SIRPA,JUP,CDH5,PLEC,CDH6,PARVB,KIRREL3,PVRL1A,F11R.2,KIRREL2
    Cell-extracellular matrix interactions LIMS1,ITGB1B.1,TESK1,RSU1,FERMT2,PARVB
    Cell junction organization DST,ITGB1B.1,CLDN20,CDH6,CDH10,CDH18,CDH12,CDH17,CADM2A,CDH18A

    Protein Function

    FBLIM1 has several biochemical functions, for example, filamin binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBLIM1 itself. We selected most functions FBLIM1 had, and list some proteins which have the same functions with FBLIM1. You can find most of the proteins on our site.

    Function Related Protein
    filamin binding HSPB7,PDLIM2,FAM101A,MICALL2,ZNF664-FAM101A,TMEM67,FAM101B,NEBL
    zinc ion binding RXRAA,GATA2,MKRN4,ZNF34,ZRANB1,TMEM163,FHL3B,FHL1B,WBP4,ACE2
    protein binding BCL2A1,PDCD5,BMP4,FKBP6,CLN5,LAMTOR1,FBXO4,O3far1,EFNA1,OSTB

    Interacting Protein

    FBLIM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBLIM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBLIM1.

    CUTA;HIST1H3D;LMO3;let-756

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