FATE1
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Official Full Name
fetal and adult testis expressed 1 -
Overview
This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. -
Synonyms
FATE1;fetal and adult testis expressed 1;fetal and adult testis-expressed transcript protein;cancer/testis antigen 43;CT43;FATE;BJ-HCC-2 antigen;tumor antigen BJ-HCC-2;fetal and adult testis expressed transcript protein
Recombinant Proteins
- Rhesus macaque
- Human
- Bovine
- Mus musculus
- Sus scrofa (Pig)
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- E.coli expression system
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
FATE1 involved in several pathways and played different roles in them. We selected most pathways FATE1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FATE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FATE1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FATE1 itself. We selected most functions FATE1 had, and list some proteins which have the same functions with FATE1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MKNK2,CAST,TBC1D2,SGOL1,METTL21C,LYAR,EIF3C,CCNB3,CSTF1,ASCL3 |
Interacting Protein
FATE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FATE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FATE1.
EMD;BIK;NRG4;7809;SYNGR1;BNIP3L
Resources
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References
- Khosravi-Farsani, S; Amidi, F; et al. Isolation and Enrichment of Mouse Female Germ Line Stem Cells. CELL JOURNAL 16:406-415(2015).
- Kvist, K; Clasen-Linde, E; et al. Adult Immunohistochemical Markers Fail to Detect Intratubular Germ Cell Neoplasia in Prepubertal Boys with Cryptorchidism. JOURNAL OF UROLOGY 191:1084-1089(2014).
