FAF1
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Official Full Name
Fas (TNFRSF6) associated factor 1 -
Overview
FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TR -
Synonyms
FAF1;Fas (TNFRSF6) associated factor 1;FAS-associated factor 1;CGI 03;hFAF1;HFAF1s;TNFRSF6 associated factor 1;UBX domain protein 3A;UBXD12;UBXN3A;TNFRSF6-associated factor 1;UBX domain-containing protein 12;UBX domain-containing protein 3A;C
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- Mammalian cells
- E.coli
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
FAF1 involved in several pathways and played different roles in them. We selected most pathways FAF1 participated on our site, such as FAS pathway and Stress induction of HSP regulation,RB in Cancer,TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TNF-alpha/NF-kB Signaling Pathway | TNIP1,TRPC4AP,PAPOLA,KIAA1967,PPP1R13L,TANK,TIFA,NKIRAS2,RNF25,TRAIP |
| RB in Cancer | DCK,SMARCA2,RABIF,HMGB2,HLTF,RBP1,ANLN,TOP2A,PRMT2 |
| FAS pathway and Stress induction of HSP regulation | LMNB2,DFFA,DAXX |
Protein Function
FAF1 has several biochemical functions, for example, NF-kappaB binding,heat shock protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAF1 itself. We selected most functions FAF1 had, and list some proteins which have the same functions with FAF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NF-kappaB binding | RNF25,ANXA4,HDAC2,BCL10,HIF1AN,BRMS1,SNAI1A,RELA,HDAC1,EP300 |
| protein kinase regulator activity | KIDINS220,CDK5RAP1,CSNK2B,CDC37,RAC2,ANKRD54,APC,KIDINS220B |
| heat shock protein binding | DNAJA3B,IRAK1,DNAJA3,NFKBIA,BAK1,TFAM,FKBP4,HSPA8,GRXCR2,CDC37 |
| ubiquitin protein ligase binding | DERL1,FZD5,CD40,UBE2V2,SPG20,PTPN22,UBE2Z,CCT2,ATP6V0C,DAXX |
| ubiquitin binding | FAM125A,NPLOC4,VPS36,UBXN1,UCHL3,RNF168,C6orf106,C36E6.2,NSFL1C,FAN1 |
| protein kinase binding | SKAP1,PAX6,PAK2,RFFL,GPRC5B,CEP68,GOLGA2,FAM83D,PEBP1,PTPRR |
| protein domain specific binding | GUSB,YWHAQ,HIST1H4E,YWHAG1,YWHAQB,MED12,RAPGEF3,DIXDC1,FOXH1,RAB6A |
| protein binding | MNDA,MAGEA3,MED1,SLU7,KIF18B,ECE2,C14orf93,ELK1,EPHB6,YWHAQ |
Interacting Protein
FAF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAF1.
VCP;NPLOC4;UFD1L;PLAA;CHM;G3BP1;SCHIP1;ITGB1BP1;IGF2;ANXA1;TK1;UROD;HSPA1A;SKIL;TNNT1;RCC1
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