FADS1
-
Official Full Name
fatty acid desaturase 1 -
Overview
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. -
Synonyms
FADS1;fatty acid desaturase 1;LLCDL1;D5D;delta 5 desaturase;FADS6;FADSD5;TU12;delta-5 desaturase;delta(5) desaturase;delta-5 fatty acid desaturase;delta(5) fatty acid desaturase;linoleoyl-CoA desaturase (delta-6-desaturase)-like 1;FLJ38956;F
Recombinant Proteins
- Human
- Rat
- Mouse
- Mus musculus
- Papio anubis (Olive baboon)
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
FADS1 involved in several pathways and played different roles in them. We selected most pathways FADS1 participated on our site, such as Biosynthesis of unsaturated fatty acids,Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FADS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty acid metabolism | ACSBG1,OXSM,ACSBG2,PTPLAD1,ACSL1,CPT2,PECR,MECR,ACACA,ELOVL6 |
| Biosynthesis of unsaturated fatty acids | ACAA1,HSD17B12,SCD5,ACAA1A,ELOVL6,BAAT,PTPLA,HADHA,HSD17B12B,ACOT7 |
Protein Function
FADS1 has several biochemical functions, for example, C-5 sterol desaturase activity,oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FADS1 itself. We selected most functions FADS1 had, and list some proteins which have the same functions with FADS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| C-5 sterol desaturase activity | SC5DL |
| oxidoreductase activity | AKR1E1,CYP2X8,AKR1A1B,TECRL,CYP1C2,CYP2AA1,RYROXD1,CYP2V1,CYP4A10,SDR39U1 |
Interacting Protein
FADS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FADS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FADS1.
q65zq1_human;PAAF1;DHCR7;CCDC22
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