EXT1
-
Official Full Name
exostosin 1
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- Mus musculus
- Bovine
- Papio anubis (Olive baboon)
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EXT1-2682H | Recombinant Human EXT1 protein, His-tagged | E.coli | Human | His | 435-573 aa | |
| EXT1-3274H | Recombinant Human EXT1 protein, His-tagged | E.coli | Human | His | 36-330 aa | |
| EXT1-412H | Recombinant Human EXT1 Protein, His-tagged | E.coli | Human | His | Cys334~Arg549 | |
| EXT1-1524R | Recombinant Rhesus monkey EXT1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
|
|
| EXT1-3583H | Recombinant Human EXT1 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| EXT1-5391M | Recombinant Mouse EXT1 Protein | Mammalian Cell | Mouse | His |
|
|
| EXT1-6497HCL | Recombinant Human EXT1 293 Cell Lysate | HEK293 | Human | Non |
|
|
| EXT1-1349R | Recombinant Rhesus Macaque EXT1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
|
|
| EXT1-1349R-B | Recombinant Rhesus Macaque EXT1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
|
||
| EXT1-2908M | Recombinant Mouse EXT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| EXT1-2908M-B | Recombinant Mouse EXT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| EXT1-4446HF | Recombinant Full Length Human EXT1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 746 amino acids |
|
| RFL18736MF | Recombinant Full Length Mouse Exostosin-1(Ext1) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-746) |
|
| RFL27068BF | Recombinant Full Length Bovine Exostosin-1(Ext1) Protein, His-Tagged | E.coli expression system | Bovine | His | Full L. Full Length (1-746) |
|
| RFL32034PF | Recombinant Full Length Papio Anubis Exostosin-1(Ext1) Protein, His-Tagged | E.coli expression system | Papio anubis (Olive baboon) | His | Full L. Full Length (1-746) |
|
Involved Pathway
EXT1 involved in several pathways and played different roles in them. We selected most pathways EXT1 participated on our site, such as Glycosaminoglycan biosynthesis - heparan sulfate / heparin,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | DHODH,GBE1,HSD17B3,NANP,GRHPRA,HIBCH,ST6GAL2A,INPP4B,AOX3L1,PANK2 |
| Glycosaminoglycan biosynthesis - heparan sulfate / heparin | HS2ST1A,HS3ST3B1,EXT1B,HS3ST2,EXT2,B4GALT7,HS3ST1,HS6ST1B,HS2ST1,MAPK1IP1L |
Protein Function
EXT1 has several biochemical functions, for example, N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity,acetylglucosaminyltransferase activity,glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EXT1 itself. We selected most functions EXT1 had, and list some proteins which have the same functions with EXT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity | EXT1C,EXTL1,EXT1B,EXT1A,EXT2 |
| metal ion binding | CSNK2B,C2,FHL2A,POLI,FGD,EXTL3,ROCK1,EGR2A,PAPOLB,ZNF777 |
| acetylglucosaminyltransferase activity | C3orf39,MGAT1,MGAT1B,GALNT18A,GCNT4A,HEXB,GTDC2,OGT,HEXA,MGAT1A |
| glucuronosyltransferase activity | UGT5C3,UGT2B7,UGT3A1,UGT2B6,UGT1A6A,UGT1A7,GYLTL1B,CSGALNACT1,UGT5A3,UGT1A7C |
| protein heterodimerization activity | MEIS1,TTR,HIST1H4I,TENM2,CHRAC1,HIST1H2AM,SOX15,PVALB,BMP7A,IKBKB |
| N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity | EXT1A,EXT1B,EXT1C,EXT2 |
| protein homodimerization activity | CREB3,XDH,SETMAR,PTPRE,CTBP1,TBX15,S100A1,CBS,VPS24,SIAH1A |
| heparan sulfate N-acetylglucosaminyltransferase activity | EXT2 |
| transferase activity, transferring glycosyl groups | GLT8D1,UGT8A,UGGT1,A3GALT2,UGT5C3,UGT2A6,B3GNT5A,EXT1B,B3GAT1A,B3GNT2B |
Interacting Protein
EXT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXT1.
MYH1;CNTF;OSTF1;fdhF;Kif2c
Resources
Related Services
Related Products
References
- Nadanaka, S; Kagiyama, S; et al. Roles of EXTL2, a member of the EXT family of tumour suppressors, in liver injury and regeneration processes. BIOCHEMICAL JOURNAL 454:133-145(2013).
- Multhaupt, HAB; Couchman, JR; et al. Heparan Sulfate Biosynthesis: Methods for Investigation of the Heparanosome. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 60:908-915(2012).
