EXOSC3

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  • Overview
  • Review / Q&A
  • Official Full Name

    exosome component 3
  • Overview

    Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex.
  • Synonyms

    EXOSC3;exosome component 3;exosome complex component RRP40;CGI 102;CGI 102 protein;exosome component Rrp40;hRrp 40;hRrp40p;p10;RRP40;Rrp40p;exosome complex exonuclease RRP40;ribosomal RNA-processing protein 40;CGI-102;hRrp-40;bA3J10.7;MGC7

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
EXOSC3-12596H Recombinant Human EXOSC3, GST-tagged E.coli Human GST 1-275a.a.
EXOSC3-1521R Recombinant Rhesus monkey EXOSC3 Protein, His-tagged Mammalian Cells Rhesus macaque His
EXOSC3-210H Recombinant Human EXOSC3, His-tagged E.coli Human His 1-275aa
EXOSC3-3189Z Recombinant Zebrafish EXOSC3 Mammalian Cells Zebrafish His
EXOSC3-3571H Recombinant Human EXOSC3 Protein, GST-tagged Wheat Germ Human GST
EXOSC3-4355C Recombinant Chicken EXOSC3 Mammalian Cells Chicken His
EXOSC3-6502HCL Recombinant Human EXOSC3 293 Cell Lysate HEK293 Human Non
EXOSC3-1346R Recombinant Rhesus Macaque EXOSC3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
EXOSC3-1346R-B Recombinant Rhesus Macaque EXOSC3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Exosc3-2891M Recombinant Mouse Exosc3 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
EXOSC3-4429HF Recombinant Full Length Human EXOSC3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 275 amino acids

Involved Pathway

EXOSC3 involved in several pathways and played different roles in them. We selected most pathways EXOSC3 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOSC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA degradation CNOT4B,SKIV2L,LSM7,PFKP,PABPC1L2A,DnaK,BTG3,CNOT2,EXOSC4,CNOT6

Protein Function

EXOSC3 has several biochemical functions, for example, 3-5-exoribonuclease activity,RNA binding,NOT exoribonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOSC3 itself. We selected most functions EXOSC3 had, and list some proteins which have the same functions with EXOSC3. You can find most of the proteins on our site.

Function Related Protein
3-5-exoribonuclease activity REXO2,TOE1,DOM3Z,DIS3L2,CNOT8,DIS3L,DIS3,PNPT1,C16orf57,ISG20
protein binding EIF3I,ABLIM1,PFDN2,BRSK1,ACHE,USP37,TTC1,ZFYVE20,MLLT10,VAMP5
RNA binding DPPA5,DAZL,RBM24A,EIF2C3,PPARGC1B,QKI2,CPSF1,WRAP53,RPL31,SMARCE1
NOT exoribonuclease activity EXOSC8,EXOSC4,EXOSC5,EXOSC2,EXOSC7,EXOSC1

Interacting Protein

EXOSC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOSC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOSC3.

EXOSC2;EXOSC4;EXOSC5;DIS3L

Resources

References

  • Ansari, D; Andersson, R; et al. Protein deep sequencing applied to biobank samples from patients with pancreatic cancer. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 141:369-380(2015).
  • Weitzer, S; Hanada, T; et al. CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders. WILEY INTERDISCIPLINARY REVIEWS-RNA 6:47-63(2015).

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