EXOSC3
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- Overview
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Official Full Name
exosome component 3 -
Overview
Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. -
Synonyms
EXOSC3;exosome component 3;exosome complex component RRP40;CGI 102;CGI 102 protein;exosome component Rrp40;hRrp 40;hRrp40p;p10;RRP40;Rrp40p;exosome complex exonuclease RRP40;ribosomal RNA-processing protein 40;CGI-102;hRrp-40;bA3J10.7;MGC7
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EXOSC3-12596H | Recombinant Human EXOSC3, GST-tagged | E.coli | Human | GST | 1-275a.a. | |
| EXOSC3-1521R | Recombinant Rhesus monkey EXOSC3 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| EXOSC3-210H | Recombinant Human EXOSC3, His-tagged | E.coli | Human | His | 1-275aa |
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| EXOSC3-3189Z | Recombinant Zebrafish EXOSC3 | Mammalian Cells | Zebrafish | His |
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| EXOSC3-3571H | Recombinant Human EXOSC3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EXOSC3-4355C | Recombinant Chicken EXOSC3 | Mammalian Cells | Chicken | His |
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| EXOSC3-1346R | Recombinant Rhesus Macaque EXOSC3 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| Exosc3-2891M | Recombinant Mouse Exosc3 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| EXOSC3-4429HF | Recombinant Full Length Human EXOSC3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 275 amino acids |
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Involved Pathway
EXOSC3 involved in several pathways and played different roles in them. We selected most pathways EXOSC3 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOSC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | PABPC1L,CNOT1,PAN3,PABPC3,BTG2,CNOT2,CNOT4,ENO1,PABPC1,SKIV2L |
Protein Function
EXOSC3 has several biochemical functions, for example, 3-5-exoribonuclease activity,RNA binding,NOT exoribonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOSC3 itself. We selected most functions EXOSC3 had, and list some proteins which have the same functions with EXOSC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NOT exoribonuclease activity | EXOSC2,EXOSC8,EXOSC4,EXOSC7,EXOSC5,EXOSC1 |
| RNA binding | MRPL23,IFIT5,UNC50,RBM6,KHDC1C,THOC1,CNOT8,HNRNPH1,RPLP1,HNRNPA2B1 |
| 3-5-exoribonuclease activity | ERI3,PNPT1,CNOT7,C16orf57,TOE1,DIS3L,CNOT8,EXOSC7,USB1,DOM3Z |
| protein binding | IL6ST,SEPT12,CLIC2,AMHR2,IK,BAZ2A,KLRC2,MOCS3,AP5S1,MTF1 |
Interacting Protein
EXOSC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOSC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOSC3.
EXOSC2;EXOSC4;EXOSC5;DIS3L
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References
- Ansari, D; Andersson, R; et al. Protein deep sequencing applied to biobank samples from patients with pancreatic cancer. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 141:369-380(2015).
- Weitzer, S; Hanada, T; et al. CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders. WILEY INTERDISCIPLINARY REVIEWS-RNA 6:47-63(2015).
