EPB41

  • Official Full Name

    erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)

  • Overview

    The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

  • Synonyms

    EPB41;erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked);EL1;protein 4.1;4.1R;P4.1;EPB4.1;band 4.1;erythrocyte surface protein band 4.1;HE

Recombinant Proteins

  • Human
  • Chicken
  • Mouse
  • Wheat Germ
  • Mammalian Cell
  • In Vitro Cell Free System
  • HEK293T
  • E.coli
  • Non
  • GST
  • His
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
EPB41-28575TH Recombinant Human EPB41 Wheat Germ Human Non 720 amino acids
EPB41-3351H Recombinant Human EPB41 Protein, GST-tagged Wheat Germ Human GST
EPB41-4036C Recombinant Chicken EPB41 Mammalian Cell Chicken His
EPB41-560HCL Recombinant Human EPB41 cell lysate Human Non
EPB41-157HF Recombinant Full Length Human EPB41 Protein In Vitro Cell Free System Human Full L. 720 amino acids
EPB41-3551H Recombinant Human EPB41 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
EPB41-4350HF Recombinant Full Length Human EPB41 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 720 amino acids
EPB41-468H Recombinant Human EPB41 Protein, His-tagged E.coli Human His Met210~Lys497
Epb41-469M Recombinant Mouse Epb41 Protein, His-tagged E.coli Mouse His Met211~Lys498

    Involved Pathway

    EPB41 involved in several pathways and played different roles in them. We selected most pathways EPB41 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPB41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Tight junction MYHC4,SYMPK,VAPAL,MYL9B,KRAS,CLDN16,MYH6,HCLS1,CLDN19,GNAI1

    Protein Function

    EPB41 has several biochemical functions, for example, 1-phosphatidylinositol binding,actin binding,calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPB41 itself. We selected most functions EPB41 had, and list some proteins which have the same functions with EPB41. You can find most of the proteins on our site.

    Function Related Protein
    spectrin binding USH1C,MYO7A,SLC26A5,PDE6G,GBP1,DYNC1I1,PTPRN,MYO10,DCTN2,ADD2
    calmodulin binding NOS2,MYO9B,STRN4,MYH9,SLC14A2,ADCY3,KCNN1B,KCNH5,SCN5A,AEBP1
    actin binding SPTAN1,GIPC1,MACF1,TPMA,CAPZA3,PAWR,WASF1,SHROOM2,PIP,DST
    protein binding CCP110,ADRA2B,LHX9,MAGI2,PVRL1,LOC149950,PLLP,PSME3,SAMD4A,TSPAN15
    1-phosphatidylinositol binding WDFY3,MCF2L,SYT1,PICALM,SNAP91,PICALMA,ZFYVE9,ZFYVE1,SNX10,SCARB1
    structural constituent of cytoskeleton EPB41L3,CTNNA2,TUBAL3,KRT14,TUBA4A,ACTA1,TUBE1,TUBG1,SORBS2,TNNT2A

    Interacting Protein

    EPB41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPB41 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPB41.

    CASK;4504555;CLIC1;PSMA7;PFAS;SNX3;SNRNP200;NUP155;ATP5L;PNP;HPRT1;GOT2;CSTB;GYPC;TPM2;TXN;COX5B;PCNA

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