ELF4
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Official Full Name
E74-like factor 4 (ets domain transcription factor) -
Overview
The protein encoded by this gene is a transcriptional activator that binds and activates the promoters of the CSF2,;IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate;immunity, and induction of cell cycle arrest in naive CD8+ cells. Two transcript variants encoding the same protein;have been found for this gene. -
Synonyms
ELF4;E74-like factor 4 (ets domain transcription factor);ETS-related transcription factor Elf-4;ELFR;MEF;myeloid Elf-1-like factor
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ELF4-12401H | Recombinant Human ELF4, His-tagged | E.coli | Human | His | 1-301a.a. | |
| ELF4-2984H | Recombinant Human ELF4 protein, His-tagged | E.coli | Human | His | 301 - 515 aa | |
| ELF4-3242H | Recombinant Human ELF4 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ELF4-5130M | Recombinant Mouse ELF4 Protein | Mammalian Cell | Mouse | His |
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| ELF4-6631HCL | Recombinant Human ELF4 293 Cell Lysate | HEK293 | Human | Non |
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| ELF4-2735M | Recombinant Mouse ELF4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ELF4-2735M-B | Recombinant Mouse ELF4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ELF4 involved in several pathways and played different roles in them. We selected most pathways ELF4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ELF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ELF4 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein binding,transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELF4 itself. We selected most functions ELF4 had, and list some proteins which have the same functions with ELF4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | ELK3,AGO1,MYPOP,ALS2CR8,MYF5,ATF3,ATF4,ZNF100,FOSL1A,NFATC2 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | FOXA1,MYBL1,POU2F2,GATA1,POU4F2,EBF4,TRP53,ARID3B,NFAT5,DLX3 |
| protein binding | TRIM27,SLC30A3,CCDC87,C17orf82,NCOA1,RBMS1,SECISBP2,SPAST,HHLA2,RHOT1 |
Interacting Protein
ELF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELF4.
RUNX1;CASP4;SET;hmp
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