EIF3I
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Official Full Name
eukaryotic translation initiation factor 3, subunit I -
Overview
The elF3I (eIF3-p36) is a subunit of eukaryotic translation initiation factor 3 (eIF3) complex that plays a central role in the protein translation initiation. The eIF3 consists of at least 10 subunits ranging from 35 to 170 kd. elF3-p36 is constitutively -
Synonyms
EIF3I;eukaryotic translation initiation factor 3, subunit I;EIF3S2, eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa;eukaryotic translation initiation factor 3 subunit I;eIF3 beta;eIF3 p36;TRIP 1;eIF-3-beta;predicted prote
Recombinant Proteins
- Zebrafish
- Human
- Rat
- Chicken
- Mouse
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- E. coli
- His
- T7
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
EIF3I involved in several pathways and played different roles in them. We selected most pathways EIF3I participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3I were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | SEH1L,EIF2B3,DDX39B,CYFIP2,PABPC4,EIF3G,EIF4E1C,EIF3B,EIF2B1,SIP1 |
Protein Function
EIF3I has several biochemical functions, for example, poly(A) RNA binding,protein binding,contributes_to translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3I itself. We selected most functions EIF3I had, and list some proteins which have the same functions with EIF3I. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HIRIP3,AHSA1,ZDHHC17,TP73,UTP3,GSTK1,FLI1,SGCG,ECE2,GALNT3 |
| poly(A) RNA binding | KIAA1324,KTN1,HSPA9,DHX30,ZFP36,DDX24,EIF4G2,HNRNPH3,USO1,RPL18A |
| contributes_to translation initiation factor activity | EIF2B4,EIF3M,EIF3B,EIF3HA,EIF3L,EIF3EA,EIF3S10,EIF3HB,EIF2B1,EIF3K |
Interacting Protein
EIF3I has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3I here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3I.
EIF3B;Eif3a;CLEC4G;gag-pol;SGK1;EIF3H;EIF1B;GH1;TFE3;MCC;HLA-B;EIF6;ACTB
Resources
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References
- Rezende, AM; Assis, LA; et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates - identification of conserved and divergent features based on orthologue analysis. BMC GENOMICS 15:-(2014).
- Yuan, YK; Zhang, YG; et al. The Translation Initiation Factor eIF3i Up-regulates Vascular Endothelial Growth Factor A, Accelerates Cell Proliferation, and Promotes Angiogenesis in Embryonic Development and Tumorigenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 289:28310-28323(2014).
