EIF2B4
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Official Full Name
eukaryotic translation initiation factor 2B, subunit 4 delta
Recombinant Proteins
- Rat
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- His
- GST
- Myc&DDK
- Non
- His&Fc&Avi
Involved Pathway
EIF2B4 involved in several pathways and played different roles in them. We selected most pathways EIF2B4 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2B4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | EIF3EA,NUP155,EIF4A3,SUMO2,EIF2B1,PABPC1L2A,NUP85,POM121L2,NCBP2,EIF3I |
Protein Function
EIF2B4 has several biochemical functions, for example, NOT S-methyl-5-thioribose-1-phosphate isomerase activity,contributes_to guanyl-nucleotide exchange factor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2B4 itself. We selected most functions EIF2B4 had, and list some proteins which have the same functions with EIF2B4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NOT S-methyl-5-thioribose-1-phosphate isomerase activity | EIF2B1,EIF2B3,EIF2B2 |
| contributes_to translation initiation factor activity | EIF3F,EIF3E,EIF3I,EIF3S6IP,EIF3G,EIF3J,EIF2B3,EIF3C,EIF3S10,EIF2B5 |
| contributes_to guanyl-nucleotide exchange factor activity | LAMTOR3,LAMTOR1,EIF2B1,LAMTOR2,ALS2,EIF2B3,C7orf59,HBXIP,EIF2B5,EIF2B2 |
| protein binding | BCL2L11,KCNH2,ANO2,CTDSP2,ZFYVE19,SEPT1,CHRM3,CDC6,STT3A,FRA10AC1 |
| translation initiation factor binding | TRIM32,EIF3M,POLR2D,DDX3X,RPS24,LIN28A,EIF3BA,EIF3F,CELF1,LARP1 |
Interacting Protein
EIF2B4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2B4 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2B4.
EIF2B2;UBE2F;pi3p;NSS;DCC;NS;CDC5L;AGO1;EPB41L3
Resources
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References
- Xue, DB; Lu, M; et al. Screening for transcription factors and their regulatory small molecules involved in regulating the functions of CL1-5 cancer cells under the effects of macrophage- conditioned medium. ONCOLOGY REPORTS 31:1323-1333(2014).
- Zucchini-Pascal, N; de Sousa, G; et al. Molecular investigation of the effects of lindane in rat hepatocytes: Microarray and mechanistic studies. FOOD AND CHEMICAL TOXICOLOGY 49:3128-3135(2011).
