EFS
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Official Full Name
embryonal Fyn-associated substrate -
Overview
The protein encoded by this gene contains a SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to be able to bind to SH3 domain of protein-tyrosine kinases. The function of this gene is unknown. Two alternatively spliced variants have been described. -
Synonyms
EFS;embryonal Fyn-associated substrate;Cas scaffolding protein family member 3;CASS3;EFS1;EFS2;HEFS;SIN;CAS3;Embryonal Fyn associated substrate;signal transduction protein (SH3 containing)
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EFS-3108H | Recombinant Human EFS Protein, GST-tagged | Wheat Germ | Human | GST |
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| EFS-5038M | Recombinant Mouse EFS Protein | Mammalian Cell | Mouse | His |
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| EFS-6699HCL | Recombinant Human EFS 293 Cell Lysate | HEK293 | Human | Non |
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| EFS-2673M | Recombinant Mouse EFS Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| EFS-2673M-B | Recombinant Mouse EFS Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Efs-2757M | Recombinant Mouse Efs Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| EFS-3849H | Recombinant Human EFS Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| EFS-4238HF | Recombinant Full Length Human EFS Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 468 amino acids |
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Involved Pathway
EFS involved in several pathways and played different roles in them. We selected most pathways EFS participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EFS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
EFS has several biochemical functions, for example, SH3 domain binding,protein binding,protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EFS itself. We selected most functions EFS had, and list some proteins which have the same functions with EFS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH3 domain binding | SGIP1,REPS1,ARHGAP31,SH3BP5,SHANK1,CYBA,PLSCR4,PTPN12,QKI,VASP |
| protein domain specific binding | HIST1H4H,TUBA1A,ARR3,HIST1H4I,IKBKG,HIST1H4N,FOXA2,PHRF1,ATN1,VRK2 |
| protein binding | LCA5,ARL3,HNF1B,CATSPERB,CCNL1,PRDM16,EMD,COL17A1,PDGFRB,LRPAP1 |
Interacting Protein
EFS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFS here. Most of them are supplied by our site. Hope this information will be useful for your research of EFS.
NUP155;SORBS2;FYN;ZNF417;OSTF1;TSSK1B;ABI2
Resources
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References
- Ramani, P; Nash, R; et al. Aurora kinase A is superior to Ki67 as a prognostic indicator of survival in neuroblastoma. HISTOPATHOLOGY 66:370-379(2015).
- Coquenlorge, S; Duchalais, E; et al. Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system. JOURNAL OF NEUROINFLAMMATION 11:-(2014).
