Dmgdh
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Official Full Name
dimethylglycine dehydrogenase
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DMGDH-2705H | Recombinant Human DMGDH Protein, GST-tagged | Wheat Germ | Human | GST |
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| DMGDH-4645M | Recombinant Mouse DMGDH Protein | Mammalian Cell | Mouse | His |
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| DMGDH-2411M | Recombinant Mouse DMGDH Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DMGDH-2411M-B | Recombinant Mouse DMGDH Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Dmgdh involved in several pathways and played different roles in them. We selected most pathways Dmgdh participated on our site, such as Glycine, serine and threonine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Dmgdh were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycine, serine and threonine metabolism | SDSL,GRHPRB,PSAT1,LSM1,SARDH,MAOB,PGAM1B,MAOA,DAO,AOC3 |
| Metabolic pathways | RDH8B,HDC,DNMT3B,QDPRB2,ACLYA,LPCAT2,AMY2A,CYP3A41A,GNS,IVD |
Protein Function
Dmgdh has several biochemical functions, for example, dimethylglycine dehydrogenase activity,flavin adenine dinucleotide binding,folic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Dmgdh itself. We selected most functions Dmgdh had, and list some proteins which have the same functions with Dmgdh. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidoreductase activity | SCD5,RDH7,CYP2AA6,HSD17B12B,CHML,RDH10A,FADS6,SDR42E1,EGLN1B,RETSATL |
| flavin adenine dinucleotide binding | TXNRD1,NOS1,DLD,DPYD,CHDH,GSR,MAOA,CYBB,AOX1,TXNRD2 |
| poly(A) RNA binding | C3orf26,TOP3B,EIF4E2,YTHDF2,POLR2B,EMG1,ARCN1,CSTF3,TNS1,EIF3A |
| folic acid binding | DAAM2,FOLR2,SLC19A1,FOLR3,TYMS,SLC46A1,FTCD,GNMT,MTHFS,DHFR |
Interacting Protein
Dmgdh has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Dmgdh here. Most of them are supplied by our site. Hope this information will be useful for your research of Dmgdh.
Ywhae;Hsd3b4
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References
- Morrow, GP; MacMillan, L; et al. In Vivo Kinetics of Formate Metabolism in Folate-deficient and Folate-replete Rats. JOURNAL OF BIOLOGICAL CHEMISTRY 290:2244-2250(2015).
- Luka, Z; Pakhomova, S; et al. Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 449:392-398(2014).
