DUSP12
-
Official Full Name
dual specificity phosphatase 12 -
Overview
MAP kinases are inactivated by a family of dual-specificity protein phosphatases (DUSP) that differ in their substrate specificity, tissue distribution, inducibility by extracellular stimuli and cellular localization. DUSP1/MKP1 (MAP Kinase phosphatase 1) -
Synonyms
DUSP12;dual specificity phosphatase 12;dual specificity protein phosphatase 12;DUSP1;serine/threonine specific protein phosphatase;YVH1;YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog;YVH1 protein-tyrosine phosphatase ortholog;dual spec
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- Mammalian cells
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
- Flag
Involved Pathway
DUSP12 involved in several pathways and played different roles in them. We selected most pathways DUSP12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DUSP12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DUSP12 has several biochemical functions, for example, kinase binding,protein binding,protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DUSP12 itself. We selected most functions DUSP12 had, and list some proteins which have the same functions with DUSP12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein tyrosine phosphatase activity | PTPRJA,DUSP13A,MTM1,EYA1,PTPN4B,DUSP16,PTP4A1,PTPRJ,PTENA,DUSP22 |
| protein tyrosine/serine/threonine phosphatase activity | PXYLP1,EPM2A,DUSP8A,DUSP23A,LRP8,PTP4A1,TPTE,DUSP3B,NT5DC3,RNGTT |
| protein binding | GSTO2,GAPDH,SIN3A,PLGRKT,PAX8,RPAP3,SPOPL,GLS,PRKD1,AZU1 |
| kinase binding | PARK2,SNAI1,TNFAIP3,CEBPB,DLG3,CDC37,CHIA,JAKMIP3,MOBKL1A,CTNNB1 |
| zinc ion binding | LIMS3L,ZDHHC4,ADAMTS1,APEX2,TAB3,USP45,NR1D2B,ARIH1L,PHRF1,ZNF84 |
Interacting Protein
DUSP12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DUSP12 here. Most of them are supplied by our site. Hope this information will be useful for your research of DUSP12.
CALCOCO2;RABAC1;PPP2R3B;USO1;CCNH;EIF5
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