DRAXIN
-
Official Full Name
dorsal inhibitory axon guidance protein -
Overview
It bBelongs to the draxin family,is able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. -
Synonyms
UNQ3119;neucrin;AGPA3119;C1orf187
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian cells
- Human Cell
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- His
- GST
- His&SUMO
- His&Fc&Avi
Involved Pathway
DRAXIN involved in several pathways and played different roles in them. We selected most pathways DRAXIN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DRAXIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DRAXIN has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DRAXIN itself. We selected most functions DRAXIN had, and list some proteins which have the same functions with DRAXIN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | EEF1B2,HDAC2,LRP6,MOCS3,UBE2A,KCTD6,SUV39H1,LGI1,ORAI2,RAB3B |
Interacting Protein
DRAXIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DRAXIN here. Most of them are supplied by our site. Hope this information will be useful for your research of DRAXIN.
ntn1a;ntn1b;ntn2;NTN1
Resources
Related Services
Related Products
References
- Liu, XS; Zhang, GX; et al. Predicted Trans-Acting siRNAs in the Human Brain. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16:3377-3390(2015).
- Riyadh, MA; Shinmyo, Y; et al. Inhibitory effects of draxin on axonal outgrowth and migration of precerebellar neurons. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 449:169-174(2014).
