DPPA2
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Official Full Name
developmental pluripotency associated 2 -
Overview
DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells. -
Synonyms
DPPA2;developmental pluripotency associated 2;developmental pluripotency-associated protein 2;developmental pluripotency-associated 2;embryonic stem cell-associated transcript 15-2 protein;pluripotent embryonic stem cell-related gene 1 protein;C80932;D19Mgi18;ECAT15-2;2410088E07Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DPPA2-1324R | Recombinant Rhesus monkey DPPA2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| DPPA2-2852H | Recombinant Human DPPA2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DPPA2-6827HCL | Recombinant Human DPPA2 293 Cell Lysate | HEK293 | Human | Non |
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| DPPA2-1149R | Recombinant Rhesus Macaque DPPA2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| DPPA2-1149R-B | Recombinant Rhesus Macaque DPPA2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| DPPA2-4149HF | Recombinant Full Length Human DPPA2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 298 amino acids |
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Involved Pathway
DPPA2 involved in several pathways and played different roles in them. We selected most pathways DPPA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DPPA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
DPPA2 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by DPPA2 itself. We selected most functions DPPA2 had, and list some proteins which have the same functions with DPPA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | LRRC45,LRRC9,EDDM3B,ARXES2,TDEANC2,MARVELD2B,DNAHC8,MURCB,PLAC1,SPON2A |
Interacting Protein
DPPA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPPA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPPA2.
DVL2;SPOP;PLOD3;ZNF250;U2AF2;FXR2;DPPA4;MCM10;ZCCHC10;DVL3;PBXIP1;MOAP1;AP2M1;SETD5;SDCBP2;VTA1
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