DOCK5
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Official Full Name
dedicator of cytokinesis 5 -
Overview
Dock5 (Dedicator of cytokinesis 5), also known as DOCK5, is a large (~180 kDa) protein involved in intracellular signalling networks.It is a member of the DOCK-A subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins.Dock5 is predicted to activate the small G protein Rac. -
Synonyms
DOCK5;dedicator of cytokinesis 5;dedicator of cytokinesis protein 5;FLJ21034;DKFZp451J181;DKFZp779M164;DKFZp781J211
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Wheat Germ
- Mammalian Cell
- E.coli
- E. coli
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DOCK5-2807H | Recombinant Human DOCK5 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DOCK5-4755M | Recombinant Mouse DOCK5 Protein | Mammalian Cell | Mouse | His |
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| DOCK5-6086Z | Recombinant Zebrafish DOCK5 | Mammalian Cell | Zebrafish | His |
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| DOCK5-1367H | Recombinant Human DOCK5 Protein, His-tagged | E.coli | Human | His | Ala1749-Gln1870 |
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| DOCK5-1368H | Recombinant Human DOCK5 protein, His-tagged | E. coli | Human | His | Pro1691-Pro1840 |
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| Dock5-1368M | Recombinant Mouse Dock5 Protein, His-tagged | E.coli | Mouse | His | Met1-Leu284 |
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| DOCK5-2224H | Recombinant Human DOCK5 Protein (Arg425-Cys609), N-His tagged | E.coli | Human | His | Arg425-Cys609 |
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| DOCK5-2480M | Recombinant Mouse DOCK5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DOCK5-2480M-B | Recombinant Mouse DOCK5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
DOCK5 involved in several pathways and played different roles in them. We selected most pathways DOCK5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DOCK5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DOCK5 has several biochemical functions, for example, guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DOCK5 itself. We selected most functions DOCK5 had, and list some proteins which have the same functions with DOCK5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| guanyl-nucleotide exchange factor activity | ITSN2A,RASGEF1BA,TRIO,ARHGEF18,DIS3,FARP2,RAPGEF6,DENND4B,GCGR,RAPGEFL1 |
Interacting Protein
DOCK5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DOCK5 here. Most of them are supplied by our site. Hope this information will be useful for your research of DOCK5.
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