DNTT
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Official Full Name
deoxynucleotidyltransferase, terminal -
Overview
DNA nucleotidylexotransferase (DNTT) belongs to the DNA polymerase type-X family. DNTT catalyzes the addition of deoxynucleotides to the 3-hydroxyl terminus of oligonucleotide primers. -
Synonyms
DNTT;deoxynucleotidyltransferase, terminal;DNA nucleotidylexotransferase;TDT;Terminal deoxynucleotidyltransferase;terminal transferase;terminal addition enzyme;terminal deoxyribonucleotidyltransferase;nucleosi
Recombinant Proteins
- Bovine
- Rhesus macaque
- Zebrafish
- Human
- Mouse
- Chicken
- Cattle
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- His
- GST
- His&GST
- Non
- His&Fc&Avi
Involved Pathway
DNTT involved in several pathways and played different roles in them. We selected most pathways DNTT participated on our site, such as Hematopoietic cell lineage,Non-homologous end-joining,Validated targets of C-MYC transcriptional repression, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNTT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hematopoietic cell lineage | ITGAM,CD2,IL6,IL11RA,CD8B,FCER2,GP9,THPO,CR1,CD24 |
| Non-homologous end-joining | NHEJ1,POLM,LIG4,MRE11A,XRCC6,POLL,PRKDC,FEN1,XRCC4,XRCC5 |
| Validated targets of C-MYC transcriptional repression | ZFP36L1,CLU,LGALS1,CSDE1,S100A7,NDRG1,TMEM126A,SFXN3,GFI1,TMEFF2 |
Protein Function
DNTT has several biochemical functions, for example, DNA binding,DNA nucleotidylexotransferase activity,DNA-directed DNA polymerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DNTT itself. We selected most functions DNTT had, and list some proteins which have the same functions with DNTT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SMG9,PBXIP1,CMKLR1,CHMP1B,CACYBP,CLOCKA,THEMIS,TFF3,DPY30,HRG |
| DNA-directed DNA polymerase activity | POLD4,POLN,CCDC111,POLK,POLL,CHRAC1,POLH,POLG2,POLM,POLD2 |
| metal ion binding | MARCH5L,ZNF426,ZMYND10,ATP11A,ZNF18,VDRA,DPYDB,NEK10,ZFR,MCCC1 |
| DNA binding | CREB3,SIX7,MEF2C,PRRXL1,NR2F6A,FBXO21,IRX4A,CERS3B,ZNF404,PRKRIR |
Interacting Protein
DNTT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNTT here. Most of them are supplied by our site. Hope this information will be useful for your research of DNTT.
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