DMBX1
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Official Full Name
diencephalon/mesencephalon homeobox 1 -
Overview
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene. -
Synonyms
DMBX1;diencephalon/mesencephalon homeobox 1;orthodenticle homolog 3 (Drosophila) , OTX3;diencephalon/mesencephalon homeobox protein 1;PAXB;DMBX1_HUMAN;Homeoprotein MBX;Orthodenticle homolog 3 (Drosophila);Orthodenticle homolog 3;Paired-like homeobox protein DMBX1;Paired-like homeobox protein DMBX1-like;MBX;OTX3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DMBX1-2701H | Recombinant Human DMBX1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DMBX1-487HCL | Recombinant Human DMBX1 cell lysate | Human | Non |
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| DMBX1-4012HF | Recombinant Full Length Human DMBX1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 377 amino acids |
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Involved Pathway
DMBX1 involved in several pathways and played different roles in them. We selected most pathways DMBX1 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DMBX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neural Crest Differentiation | LHX1,CDH7,CTBP2,DCT,TFAP2A,CDH6,GBX2,OLIG3,OLIG2,TBX6 |
Protein Function
DMBX1 has several biochemical functions, for example, DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DMBX1 itself. We selected most functions DMBX1 had, and list some proteins which have the same functions with DMBX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | MCL1A,BAD,MEF2C,HIST4H4,AHR,TAF13,CD3G,SLC3A1,PRPH,TYRP1 |
| transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | JARID2,CHCHD3,POU5F1,ETV6,HOXD9,VAX2,CDX2,MNT,PURB,MITF |
| sequence-specific DNA binding | NR4A2B,CREB3L1,PAX6B,CAMTA1,FOXF1,SIX1A,SOX2,NKX2,FOXS1,RXRA |
| protein homodimerization activity | ADD2,ALS2,PFKM,IZUMO3,FAM109A,TKT,TESC,C16orf89,PAH,SFTPC |
| DNA binding | ASCL3,SIM1A,ZBTB12,HINFP,OTPB,MKXA,CLSPN,HOXC12,RAD51L1,FOXG1 |
| transcription factor activity, sequence-specific DNA binding | LEF1,DMRTA2,SP3A,KLF10,SOX1,NR6A1A,NR2F6,SLC2A4RG,ZNF571,NKX2-6 |
| RNA polymerase II regulatory region sequence-specific DNA binding | RELA,ZBTB12.2,CREB3,ZMYND11,LYL1,FOXC1,TFAP2D,RARA,NHLH2,RORA |
Interacting Protein
DMBX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DMBX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DMBX1.
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