DLGAP4
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Official Full Name
discs, large (Drosophila) homolog-associated protein 4 -
Overview
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
DLGAP4;discs, large (Drosophila) homolog-associated protein 4;disks large-associated protein 4;DAP4;KIAA0964;SAPAP4;DAP 4;DAP-4;Disks large associated protein 4;DLGP4_HUMAN;PSD 95/SAP90 binding protein 4;PSD-95/SAP90-binding protein 4;SAP90/PSD-95-associated protein 4;SAPAP 4;SAPAP-4;DLP4;RP5-977B1.6
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DLGAP4 involved in several pathways and played different roles in them. We selected most pathways DLGAP4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DLGAP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DLGAP4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLGAP4 itself. We selected most functions DLGAP4 had, and list some proteins which have the same functions with DLGAP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TBC1D2,SEMA7A,IL10RB,WRNIP1,CST1,IL28RA,CDC42EP1,TUBGCP4,CD48,ACTN3 |
Interacting Protein
DLGAP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLGAP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLGAP4.
BIN1;ABL1;FYN;SRC;NCK1;PIK3R1;CRK;GRB2;UBB;rpoB;SH3GL2
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References
