DIS3L2
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Official Full Name
DIS3 mitotic control homolog (S. cerevisiae)-like 2 -
Synonyms
DIS3L2;DIS3 mitotic control homolog (S. cerevisiae)-like 2;FAM6A, family with sequence similarity 6, member A;DIS3-like exonuclease 2;FLJ36974;MGC42174;DIS3 L2;DIS3 mitotic control homolog (S. cerevisiae) like 2;DIS3 mitotic control homolog like 2;family with sequence similarity 6, member A;FAM6A
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293T
- Mammalian cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
DIS3L2 involved in several pathways and played different roles in them. We selected most pathways DIS3L2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DIS3L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DIS3L2 has several biochemical functions, for example, 3-5-exoribonuclease activity,magnesium ion binding,poly(U) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DIS3L2 itself. We selected most functions DIS3L2 had, and list some proteins which have the same functions with DIS3L2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | OPA1,WDR61,BIRC2,DDRGK1,HOXB9,CKB,SERPINA3K,UBOX5,GPN1,RAB9A |
| poly(U) RNA binding | RBM11,KHDRBS2,KHDC1A,MSI2,HNRNPC,MSI1,PABPC1,HNRNPH1,PABPC4,KHDRBS1 |
| magnesium ion binding | PPM1AA,STK36,PPM1A,IRAK3,MAST2,PDXK,TDP2B,COMT,AASDHPPT,PPA1A |
| ribonuclease activity | RNASEL4,EAR3,AZGP1,ANG4,RNASEH2A,EAR1,RNASEL2,RNASEL3,RNASE6,RNASE2 |
| 3-5-exoribonuclease activity | EXOSC7,CNOT8,TOE1,EXOSC5,DIS3L,USB1,PNPT1,EXOSC4,PAN2,EXOSC3 |
Interacting Protein
DIS3L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DIS3L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DIS3L2.
VIM;COPS6;FEZ1;ssdna_dn;CBX2;Wipi2;Mad2l1
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References
- Wegert, J; Ishaque, N; et al. Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors. CANCER CELL 27:298-311(2015).
- Faehnle, CR; Walleshauser, J; et al. Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. NATURE 514:252-+(2014).
