DIAPH3
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Official Full Name
diaphanous homolog 3 (Drosophila) -
Synonyms
DIAPH3;diaphanous homolog 3 (Drosophila);auditory neuropathy, autosomal dominant 1 , AUNA1, diaphanous (Drosophila, homolog) 3;protein diaphanous homolog 3;AN;DRF3;FLJ34705;NSDAN;Dia2;diap3;DKFZp434C0931;DKFZp686A13178;RP11-26P21.1;DIAP3_HUMAN;Diaphanous homolog 3;Diaphanous related formin 3;Diaphanous-related formin-3;OTTHUMP00000018480;OTTHUMP00000180577;OTTHUMP00000180578;OTTHUMP00000180579;OTTHUMP00000180580;diaphanous-related formin 3;auditory neuropathy, autosomal dominant 1;AUNA1;mDia2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DIAPH3-11993H | Recombinant Human DIAPH3, GST-tagged | E.coli | Human | GST | C-term-350a.a. | |
| DIAPH3-1483H | Recombinant Human DIAPH3 protein, His-tagged | E.coli | Human | His | 500 - 850 aa | |
| DIAPH3-1049Z | Recombinant Zebrafish DIAPH3 | Mammalian Cell | Zebrafish | His |
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| DIAPH3-2623H | Recombinant Human DIAPH3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DIAPH3-6924HCL | Recombinant Human DIAPH3 293 Cell Lysate | HEK293 | Human | Non |
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| DIAPH3-2558HF | Recombinant Full Length Human DIAPH3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 849 amino acids |
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Involved Pathway
DIAPH3 involved in several pathways and played different roles in them. We selected most pathways DIAPH3 participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with DIAPH3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Actin Cytoskeleton | EZRB,ITGAM,RRAS,FGF18,IQGAP2,ITGA5,VCLA,PFN4,PDGFRA,GNA12 |
Protein Function
DIAPH3 has several biochemical functions, for example, Rho GTPase binding,actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DIAPH3 itself. We selected most functions DIAPH3 had, and list some proteins which have the same functions with DIAPH3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | MKL1B,GMFG,PTK2,EZR,PXK,MYHZ1.2,CAPZA3,FXYD5,ACE,WIPF1 |
| Rho GTPase binding | DAPK3,KIF3B,ARHGEF16,RHOH,LRRK2,ARHGEF2,DOCK10,DOCK9,IQGAP3,ECT2 |
Interacting Protein
DIAPH3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DIAPH3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DIAPH3.
Dlg4;MYC;SIRT1;SMAD9;PTBP3;SNW1
Resources
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References
- Schoen, CJ; Burmeister, M; et al. Diaphanous homolog 3 (Diap3) Overexpression Causes Progressive Hearing Loss and Inner Hair Cell Defects in a Transgenic Mouse Model of Human Deafness. PLOS ONE 8:-(2013).
- Ji, P; Yeh, V; et al. Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 95:2013-2021(2010).
