DHX15

  • Official Full Name

    DEAH (Asp-Glu-Ala-His) box polypeptide 15

  • Overview

    The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing.

  • Synonyms

    DHX15;DEAH (Asp-Glu-Ala-His) box polypeptide 15;DDX15, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 15;putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15;DBP1;HRH2;PRP43;PRPF43;PrPp43p;ATP dependent RNA helicase #46;DDX15;DEADH box 15;DEAH (Asp Glu Ala His) box polypeptide 15;DEAH box polypeptide 15;DEAH box protein 15;RNA helicase 2;DEAD/H box-15;OTTHUMP00000217985;ATP-dependent RNA helicase #46;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 15

Recombinant Proteins

  • Rhesus macaque
  • Human
  • Chicken
  • Zebrafish
  • Mouse
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • E.coli
  • Mammalian cells
  • HEK293T
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
  • Flag
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
DHX15-1261R Recombinant Rhesus monkey DHX15 Protein, His-tagged Mammalian Cell Rhesus macaque His
DHX15-2606H Recombinant Human DHX15 Protein, GST-tagged Wheat Germ Human GST
DHX15-2829C Recombinant Chicken DHX15 Mammalian Cell Chicken His
DHX15-6551Z Recombinant Zebrafish DHX15 Mammalian Cell Zebrafish His
DHX15-6933HCL Recombinant Human DHX15 293 Cell Lysate HEK293 Human Non
DHX15-05H Recombinant Human DHX15 Protein, His-tagged E.coli Human His 147-517 a.a.
DHX15-1086R Recombinant Rhesus Macaque DHX15 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
DHX15-1086R-B Recombinant Rhesus Macaque DHX15 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
DHX15-1432HFL Recombinant Full Length Human DHX15 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
DHX15-2300H Recombinant Human DHX15 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
DHX15-2510H Recombinant Human DHX15 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
DHX15-2551HF Recombinant Full Length Human DHX15 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 199 amino acids
Dhx15-2554M Recombinant Mouse Dhx15 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
DHX15-758H Recombinant Human DHX15 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
DHX15-758H-B Recombinant Human DHX15 Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    DHX15 involved in several pathways and played different roles in them. We selected most pathways DHX15 participated on our site, such as Spliceosome,mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHX15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    mRNA processing CLK4,ZFP830,RNASET2B,RAVER1,ZFP622,D19BWG1357E,CLK2,SF3A1,LSMD1,DHX8
    Spliceosome AQR,U2AF1L4,PLRG1,U2AF2A,NCBP2,RBM17,SNRPD3L,SRSF2,HNRNPA1A,HSPA1A

    Protein Function

    DHX15 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DHX15 itself. We selected most functions DHX15 had, and list some proteins which have the same functions with DHX15. You can find most of the proteins on our site.

    Function Related Protein
    protein binding BAZ1B,AGFG1,KRT18,METTL17,RYR1B,TRIM33,CLASP1,SLC14A2,HIST2H4,SUV39H2
    double-stranded RNA binding HMGB1,TUBB4B,ILF3,BARHL1,OASL2,YRDC,OAS3,OAS1,TFRC,ELAVL1
    ATP binding NSFA,CMPK,ABCA4,PAPSS2,UBE2I,RTCD1,HSPA4B,ABCC1,TBK1,MERTK
    ATP-dependent RNA helicase activity DDX39B,DDX39,DDX43,SKIV2L,PL10,DDX21,DDX24,DHX32,DDX46,DDX3
    poly(A) RNA binding RBM27,DDX5,CALR,AHNAK,GTPBP10,SF3A1,HELZ,CLK3,ZNF207,FIP1L1
    RNA helicase activity RAD54B,DHX16,CTU1,DDX17,DDX10,UAP1L1,PRIM2,SKIV2L2,DDX5,DDX24

    Interacting Protein

    DHX15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHX15 here. Most of them are supplied by our site. Hope this information will be useful for your research of DHX15.

    RBM5;RBM17

    Resources

    References

    • Pattabhi, S; Gale, M; et al. DHX15: A novel regulator of innate immune defense to RNA virus infections. CYTOKINE 70:63-63(2014).
    • Lu, HB; Lu, N; et al. DHX15 Senses Double-Stranded RNA in Myeloid Dendritic Cells. JOURNAL OF IMMUNOLOGY 193:1364-1372(2014).

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