DHDDS
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Official Full Name
dehydrodolichyl diphosphate synthase -
Overview
The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. -
Synonyms
DHDDS;dehydrodolichyl diphosphate synthase;DS;FLJ13102;HDS;Dedol PP synthase;dedol-PP synthase;cis-prenyl transferase;cis-isoprenyltransferase;CIT;CPT;RP59
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DHDDS-12399Z | Recombinant Zebrafish DHDDS | Mammalian Cell | Zebrafish | His |
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| DHDDS-2583H | Recombinant Human DHDDS Protein, GST-tagged | Wheat Germ | Human | GST |
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| DHDDS-6948HCL | Recombinant Human DHDDS 293 Cell Lysate | HEK293 | Human | Non |
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| DHDDS-2138H | Recombinant Human DHDDS Protein (1-333 aa), GST-tagged | E.coli | Human | GST | 1-333 aa |
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| DHDDS-2524HF | Recombinant Full Length Human DHDDS Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 294 amino acids |
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| Dhdds-2543M | Recombinant Mouse Dhdds Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
DHDDS involved in several pathways and played different roles in them. We selected most pathways DHDDS participated on our site, such as Terpenoid backbone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHDDS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Terpenoid backbone biosynthesis | MVDA,HMGCRB,ACAT2,ACAT1,FDPS,MVK,HMGCS1,PDSS2,IDI2,MVD |
Protein Function
DHDDS has several biochemical functions, for example, contributes_to polyprenyltransferase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DHDDS itself. We selected most functions DHDDS had, and list some proteins which have the same functions with DHDDS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SPRED1,OTOF,SYMPK,C1orf189,GIPC2,NUAK2,CISH,OPRD1,KCND2,RIPK1L |
Interacting Protein
DHDDS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHDDS here. Most of them are supplied by our site. Hope this information will be useful for your research of DHDDS.
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