DGKK
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Official Full Name
diacylglycerol kinase, kappa -
Overview
The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. -
Synonyms
DGKK;diacylglycerol kinase, kappa;diacylglycerol kinase kappa;142 kDa diacylglycerol kinase;DAG kinase kappa;DGK kappa;Diglyceride kinase kappa;DGK-kappa
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DGKK-2576H | Recombinant Human DGKK Protein, GST-tagged | Wheat Germ | Human | GST |
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| DGKK-18H | Recombinant Active Human DGKK Protein, His-tagged | Insect Cell | Human | His |
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Involved Pathway
DGKK involved in several pathways and played different roles in them. We selected most pathways DGKK participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DGKK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DGKK has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DGKK itself. We selected most functions DGKK had, and list some proteins which have the same functions with DGKK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
DGKK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DGKK here. Most of them are supplied by our site. Hope this information will be useful for your research of DGKK.
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References
- Wheeler, ML; Dong, MB; et al. Diacylglycerol Kinase zeta Limits B Cell Antigen Receptor-Dependent Activation of ERK Signaling to Inhibit Early Antibody Responses. SCIENCE SIGNALING 6:-(2013).
- Toriumi, K; Horikoshi, Y; et al. Carbon tetrachloride-induced hepatic injury through formation of oxidized diacylglycerol and activation of the PKC/NF-kappa B pathway. LABORATORY INVESTIGATION 93:218-229(2013).
