DEDD2
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Official Full Name
death effector domain containing 2 -
Overview
Death effector domain-containing protein is a protein that in humans is encoded by the DEDD gene. This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. -
Synonyms
DEDD2;death effector domain containing 2;FLAME-3;DNA-binding death effector domain-containing protein 2;DED-containing protein FLAME-3;FADD-like anti-apoptotic molecule 3;death effector domain-containing DNA binding protein 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DEDD2-2515H | Recombinant Human DEDD2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DEDD2-4441M | Recombinant Mouse DEDD2 Protein | Mammalian Cell | Mouse | His |
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| DEDD2-6994HCL | Recombinant Human DEDD2 293 Cell Lysate | HEK293 | Human | Non |
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| DEDD2-2283M | Recombinant Mouse DEDD2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DEDD2-2283M-B | Recombinant Mouse DEDD2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| DEDD2-2418HF | Recombinant Full Length Human DEDD2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 185 amino acids |
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Involved Pathway
DEDD2 involved in several pathways and played different roles in them. We selected most pathways DEDD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DEDD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
DEDD2 has several biochemical functions, for example, DNA binding,protein binding,receptor signaling complex scaffold activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DEDD2 itself. We selected most functions DEDD2 had, and list some proteins which have the same functions with DEDD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MAP4,AAAS,SPG7,TIFA,ABCB9,LDB3,COMMD7,AZGP1,EPC1,RAB25 |
| receptor signaling complex scaffold activity | AXIN1,SHANK1,MMS19,CARD10,SPAG9,LDLRAP1,NCK2,CD3E,SPAG9A,LRRK2 |
| DNA binding | PAX7A,KIF4A,HIST1H3C,ZNF326,ATM,CROP,ZNF580,ZBTB8B,MYCLB,MEIS2A |
Interacting Protein
DEDD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEDD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DEDD2.
CDK6;ATG16L1
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