DDX39A
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Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -
Overview
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternatively spliced transcript variants encoding different isoforms have been found. -
Synonyms
DDX39A;DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A;DDX39, DEAD (Asp Glu Ala Asp) box polypeptide 39 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 39;ATP-dependent RNA helicase DDX39A;BAT1L;DDXL;UAP56 related helicase;49 kDa;URH49;DEAD box prote
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cell
- E.coli
- E.Coli or Yeast
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DDX39A involved in several pathways and played different roles in them. We selected most pathways DDX39A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX39A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DDX39A has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX39A itself. We selected most functions DDX39A had, and list some proteins which have the same functions with DDX39A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | INPP5D,POLD2,KCNG3,RAD23B,TFDP1,C16orf45,RHOG,GPR37L1,ARL16,NDEL1 |
| ATP binding | ATP8B3,DDX53,UBA5,EPHB6,AURKC,CSNK1G1,MYLK,ABCF2,MYH1E,EPHA4B |
| poly(A) RNA binding | PSPC1,CSDA,STRBP,MTHFSD,PABPC4,NUSAP1,PRDX1,HSP90AB1,DHX38,MRPL13 |
| ATP-dependent RNA helicase activity | DDX53,EIF4A1B,DHX30,DDX21,TDRD9,DHX8,DDX19,DHX38,DDX54,DDX10 |
Interacting Protein
DDX39A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX39A here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX39A.
SARNP;h0yhg0_human;SAT;TERF1;Erh;Bud13;Bles03;BABAM1;PTK2;DDX39B;TERF2
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References
- Goodier, JL; Cheung, LE; et al. MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells. PLOS GENETICS 8:-(2012).
