DDX17

  • Official Full Name

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

  • Overview

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon.

  • Synonyms

    DDX17;DEAD (Asp-Glu-Ala-Asp) box polypeptide 17;DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17 (72kD);probable ATP-dependent RNA helicase DDX17;P72;RH70;DDX17_HUMAN;DEAD (Asp Glu Ala Asp) box polypeptide 17;DEAD box protein 17;DEAD box protein p72;DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17;RNA dependent helicase p72;RNA-dependent helicase p72;OTTHUMP00000199223;OTTHUMP00000199224;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD)

Recombinant Proteins

  • Human
  • Mouse
  • HEK293
  • Wheat Germ
  • Mammalian Cell
  • Mammalian cells
  • HEK293T
  • Myc&DDK
  • Non
  • His
  • GST
  • Flag
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
DDX17-207H Recombinant Human DDX17 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
DDX17-28323TH Recombinant Human DDX17 Wheat Germ Human Non 183 amino acids
DDX17-4400M Recombinant Mouse DDX17 Protein Mammalian Cell Mouse His
DDX17-85H Recombinant Human DDX17, GST-tagged Wheat Germ Human GST
DDX17-7020HCL Recombinant Human DDX17 293 Cell Lysate HEK293 Human Non
DDX17-1039HFL Recombinant Full Length Human DDX17 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
DDX17-2264M Recombinant Mouse DDX17 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
DDX17-2264M-B Recombinant Mouse DDX17 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Ddx17-2499M Recombinant Mouse Ddx17 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
DDX17-739H Recombinant Human DDX17 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
DDX17-739H-B Recombinant Human DDX17 Protein Pre-coupled Magnetic Beads HEK293 Human

    Involved Pathway

    DDX17 involved in several pathways and played different roles in them. We selected most pathways DDX17 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    DDX17 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX17 itself. We selected most functions DDX17 had, and list some proteins which have the same functions with DDX17. You can find most of the proteins on our site.

    Function Related Protein
    estrogen receptor binding CNOT1,DDX5,PPARG,HSD17B10,PCNA,TMEM38A,PPID,WIPI1,ARRB1,PRMT2
    RNA binding PABPC1L,PRPF40B,SARNP,EIF4E1B,APOBEC3F,JAKMIP1,RPL13,RPL30,PDCD11,U2AF2A
    poly(A) RNA binding RSRC2,SPATS2,RPS23,RPS15,AGO2,DDX54,FUS,HNRNPR,COA6,PPIA
    ATP-dependent RNA helicase activity TDRD12,DHX16,DDX10,DHX9,DDX4,DDX43,DDX6,DHX38,DDX31,SUPV3L1
    RNA-dependent ATPase activity DDX39B,IGHMBP2,YTHDC2
    RNA helicase activity FAM120B,DHX9,CTU1,RAD54B,DHX15,SKIV2L2,CHST13,UAP1L1,DDX24,DDX10
    ATP binding YRK,AK7,PIM1,RPS6KA2,KIF19,HSP90AA1.1,PRKD3,DYRK4,XYLB,UBE2D4
    protein binding CIDEB,HUWE1,CTAGE5,FAM59A,TULP3,PAIP2,SLC11A2,DNM3,ARHGAP5,TRIP6
    transcription coactivator activity ING4,SP4,CALCOCO1,RARA,RNF20,BRDT,SMARCD1,KAT2A,MED14,NCOA2

    Interacting Protein

    DDX17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX17 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX17.

    ESR1;SF1;DROSHA;YAP1

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