DCTPP1
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Official Full Name
dCTP pyrophosphatase 1 -
Overview
dCTP pyrophosphatase 1 is an enzyme that in humans is encoded by the DCTPP1 gene. -
Synonyms
DCTPP1;dCTP pyrophosphatase 1;CDA03;MGC5627;RS21C6;XTP3 transactivated protein A;XTP3TPA;XTP3 transactivated gene A protein;DCTP1_HUMAN;dCTPase 1;Deoxycytidine triphosphatase 1;Deoxycytidine-triphosphatase 1;XTP3-transactivated gene A protein;XTP3-transactivated protein A
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
DCTPP1 involved in several pathways and played different roles in them. We selected most pathways DCTPP1 participated on our site, such as Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DCTPP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | Nat3,GAD2,POLR1C,CKM,NDUFB1,ALOX5,TPH1B,NT5C1B-RDH14,NMRK2,NANSA |
| Pyrimidine metabolism | NT5C1AA,UCK1,NME2B.1,NME5,POLR2K,PNP5A,NT5C2,UPRT,DPYS,POLR1E |
Protein Function
DCTPP1 has several biochemical functions, for example, dCTP diphosphatase activity,identical protein binding,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DCTPP1 itself. We selected most functions DCTPP1 had, and list some proteins which have the same functions with DCTPP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | DYNLT3,SIAH1,RAF1,USP15,TRADD,KIRRELA,CHEK2,PIP4K2C,ORAI1,ACY3 |
| magnesium ion binding | INPP1,PPM1NB,Atp8a2,ENO1A,NT5C1A,RPS6KA6,ICK,HACL1,SRPK1,NUAK2 |
| protein binding | PDZD7,MED26,PEF1,CHMP4C,APP,NAPG,TCTEX1D1,EDF1,POLB,NITR9 |
| nucleoside-triphosphate diphosphatase activity | ENPP1 |
Interacting Protein
DCTPP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCTPP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DCTPP1.
SDCBP;HLA-B;VHL;NOA1;WDYHV1;NIF3L1;bosutinib;dasatinib;PLK1;Bap1;CHMP4B
Resources
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References
- Requena, CE; Perez-Moreno, G; et al. The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells. BIOCHEMICAL JOURNAL 459:171-180(2014).
- Corson, TW; Cavga, H; et al. Triptolide Directly Inhibits dCTP Pyrophosphatase. CHEMBIOCHEM 12:1767-1773(2011).
