DAZ1
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Official Full Name
deleted in azoospermia 1 -
Overview
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains. -
Synonyms
DAZ1;deleted in azoospermia 1;DAZ, deleted in azoospermia;deleted in azoospermia protein 1;SPGY;DAZ;FLJ17175
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DAZ1-2354H | Recombinant Human DAZ1 Protein, GST-tagged | Wheat Germ | Human | GST |
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Involved Pathway
DAZ1 involved in several pathways and played different roles in them. We selected most pathways DAZ1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DAZ1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
DAZ1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DAZ1 itself. We selected most functions DAZ1 had, and list some proteins which have the same functions with DAZ1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
DAZ1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAZ1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAZ1.
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