CYP8B1
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Official Full Name
cytochrome P450, family 8, subfamily b, polypeptide 1 -
Synonyms
CP8B;CYP12
Recombinant Proteins
- Zebrafish
- Chicken
- Human
- Mouse
- Mus musculus
- Oryctolagus cuniculus (Rabbit)
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- E.coli expression system
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CYP8B1-1077Z | Recombinant Zebrafish CYP8B1 | Mammalian Cell | Zebrafish | His |
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| CYP8B1-1246C | Recombinant Chicken CYP8B1 | Mammalian Cell | Chicken | His |
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| CYP8B1-2294H | Recombinant Human CYP8B1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CYP8B1-4234M | Recombinant Mouse CYP8B1 Protein | Mammalian Cell | Mouse | His |
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| CYP8B1-2164M | Recombinant Mouse CYP8B1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CYP8B1-2164M-B | Recombinant Mouse CYP8B1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| CYP8B1-2485HF | Recombinant Full Length Human CYP8B1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 501 amino acids |
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| CYP8B1-6322H | Recombinant Human CYP8B1 protein, His-tagged | E.coli | Human | His | 22-501a.a. |
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| RFL15609MF | Recombinant Full Length Mouse 7-Alpha-Hydroxycholest-4-En-3-One 12-Alpha-Hydroxylase(Cyp8B1) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (2-500) |
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| RFL22297OF | Recombinant Full Length Rabbit 7-Alpha-Hydroxycholest-4-En-3-One 12-Alpha-Hydroxylase(Cyp8B1) Protein, His-Tagged | E.coli expression system | Oryctolagus cuniculus (Rabbit) | His | Full L. Full Length of Mature Protein (2-500) |
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Involved Pathway
CYP8B1 involved in several pathways and played different roles in them. We selected most pathways CYP8B1 participated on our site, such as Primary bile acid biosynthesis,Metabolic pathways,PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP8B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Primary bile acid biosynthesis | CYP46A1.4,AKR1C4,CYP7A1A,CYP46A1.3,BAAT,SCP2A,SCP2,AMACR,AKR1D1,HSD3B7 |
| PPAR signaling pathway | RXRB,ILK,PDPK1B,FABP7A,FABP7B,ACSBG2,FABP1A,FABP6,ACADL,PCK2 |
| Metabolic pathways | PLA2G10,GBA2,FAHD1,C1GALT1C1,GCDH,CKMT2B,POLR1D,DPM1,ADH1B,SUCLG1 |
Protein Function
CYP8B1 has several biochemical functions, for example, 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity,heme binding,iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP8B1 itself. We selected most functions CYP8B1 had, and list some proteins which have the same functions with CYP8B1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidoreductase activity | CYP2K22,CYP2C50,MOSC2,CYP46A1.4,RDH10B,CYP3A41B,DHRS12,HSD11B1LA,DIO1,HTATIP2 |
| monooxygenase activity | CYP2C18,CYP46A1.2,CYP8B3,CYP2K17,COQ6,CYP2C9,MOXD2,CYP2A12,CYP3A43,CYP2B19 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | CYP4V7,CYP1C2,PLOD1A,P4HA1B,CYP2X8,CYP21A1,CYP19A1A,CYP3C1,CYP1C1,CYP8B3 |
| heme binding | CYP2C18,SDHDB,CYP2K6,CYP2P9,CBSB,HBA-A2,CYP39A1,EPX,CYP8B3,CYP2J6 |
| iron ion binding | HBE,HBG2,CYP27A1,HBD,CYP2U1,HBBE3,SC5D,Scd1,ALOX5,CYP2AA6 |
| metal ion binding | FBXO5,CPXCR1,ZFP39,ZBTB14,KLF18,Amy1,ALPPL2,CDKAL1,ECEL1,PPARAA |
Interacting Protein
CYP8B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP8B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP8B1.
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