CYP4V2
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Official Full Name
cytochrome P450, family 4, subfamily V, polypeptide 2 -
Overview
This gene encodes a member of the cytochrome P450 hemethiolate protein superfamily which are involved in oxidizing various substrates in the metabolic pathway. It is implicated in the metabolism of fatty acid precursors into n-3 polyunsaturated fatty acids. Mutations in this gene result in Bietti crystalline corneoretinal dystrophy. -
Synonyms
CYP4V2;cytochrome P450, family 4, subfamily V, polypeptide 2;cytochrome P450 4V2;CYP4AH1;BCD;CYP4V 2;Retina CYP4V2
Recombinant Proteins
- Rhesus macaque
- Chicken
- Human
- Mus musculus
- Pongo Abelii
- Rat
- Mammalian Cell
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- E.coli expression system
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CYP4V2-1165R | Recombinant Rhesus monkey CYP4V2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| CYP4V2-1179C | Recombinant Chicken CYP4V2 | Mammalian Cell | Chicken | His |
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| CYP4V2-2287H | Recombinant Human CYP4V2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CYP4V2-440HCL | Recombinant Human CYP4V2 cell lysate | Human | Non |
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| CYP4V2-2462HF | Recombinant Full Length Human CYP4V2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 525 amino acids |
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| CYP4V2-990R | Recombinant Rhesus Macaque CYP4V2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| CYP4V2-990R-B | Recombinant Rhesus Macaque CYP4V2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| RFL16376MF | Recombinant Full Length Mouse Cytochrome P450 4V2(Cyp4V2) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-525) |
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| RFL34569PF | Recombinant Full Length Pongo Abelii Cytochrome P450 4V2(Cyp4V2) Protein, His-Tagged | E.coli expression system | Pongo Abelii | His | Full L. Full Length (1-525) |
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| RFL36768HF | Recombinant Full Length Human Cytochrome P450 4V2(Cyp4V2) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-525) |
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| RFL768RF | Recombinant Full Length Rat Cytochrome P450 4V2(Cyp4V2) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-525) |
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Involved Pathway
CYP4V2 involved in several pathways and played different roles in them. We selected most pathways CYP4V2 participated on our site, such as cytochrome P450,metapathway biotransformation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4V2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| cytochrome P450 | CYB5B,CYB5R3,CYP2A7,CYP4Z1,CYB5A,CYP2W1,CYP4F12,POR,CYP20A1 |
| metapathway biotransformation | NAA20,CHST8,GAL3ST4,KCNAB3,NAA30,CEACAM21,KCNAB2,CYP4Z1,SULT1C2,SULT6B1 |
Protein Function
CYP4V2 has several biochemical functions, for example, heme binding,iron ion binding,monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4V2 itself. We selected most functions CYP4V2 had, and list some proteins which have the same functions with CYP4V2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | CYP19A1B,CYP4V8,CYP2F2,CYP27C1,CYP2K22,CYP2X9,P4HA1B,CYP4A14,CYP46A1.1,CYP21A1 |
| heme binding | CYGB1,BA1,HBAD,CYP11B2,CYP3A7,CYP7A1,HMOX1,PGRMC2,HBB-B2,CYP3A25 |
| monooxygenase activity | CYP2F2,TYR,CYP3A25,CYP2AD2,YWHAQA,CYP4A10,CYP2AA3,CYP2P8,CYP2C55,CYP27C1 |
| iron ion binding | PAH,ISCU,NOS3,PPEF1,P4HA1A,CYP4F2,CYP21A1,OGFOD3,LCN2,CYP2C8 |
Interacting Protein
CYP4V2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4V2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4V2.
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References
- Takahashi, K; Kishimoto, Y; et al. Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1840:2289-2298(2014).
- Efstathiou, E; Titus, M; et al. Molecular Characterization of Enzalutamide-treated Bone Metastatic Castration-resistant Prostate Cancer. EUROPEAN UROLOGY 67:53-60(2015).
