CYP2D4
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Official Full Name
cytochrome P450, family 2, subfamily d, polypeptide 4 -
Overview
has N-demethylation activity toward the antidepressant imipramine. -
Synonyms
CYP2D4;cytochrome P450, family 2, subfamily d, polypeptide 4;Cyp2d18;Cyp2d4v1;CYPIID18;cytochrome P450 2d18;cytochrome P450 family 2 subfamily d polypeptide 22;Cytochrome P450 subfamily IID4;Debrisoquine 4 hydroxylase;CYPIID4;P450-DB4;P450-CMF3;P450 2D-29/2D-35;cytochrome P450 2D4;cytochrome P450-DB4;cytochrome P450-CMF3;cytochrome P450 2D-29;cytochrome P450 2D-35;debrisoquine 4-hydroxylase;Cytochrome P450, subfamily IID4;cytochrome P450, subfamily 2D, polypeptide 6;cytochrome P450, subfamily IID, polypeptide 6;cytochrome P450, family 2, subfamily d, polypeptide 22;Cyp2d6;Cyp2d22;Cyp2d4v2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Cyp2d4-138R | Active Recombinant Rat Cyp2d4 Protein | E.coli | Rat |
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| Cyp2d4-139R | Active Recombinant Rat Cyp2d4 Protein | E.coli | Rat |
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Involved Pathway
CYP2D4 involved in several pathways and played different roles in them. We selected most pathways CYP2D4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP2D4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
CYP2D4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CYP2D4 itself. We selected most functions CYP2D4 had, and list some proteins which have the same functions with CYP2D4. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
CYP2D4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP2D4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP2D4.
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References
- Bromek, E; Haduch, A; et al. The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study. EUROPEAN JOURNAL OF PHARMACOLOGY 626:171-178(2010).
