CYFIP2
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Official Full Name
cytoplasmic FMR1 interacting protein 2 -
Overview
CYFIP2 is involved in T cell adhesion and p53 dependent induction of apoptosis. It does not bind RNA but is up regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis. There are 2 isoforms produced by alternative splicing. -
Synonyms
CYFIP2;cytoplasmic FMR1 interacting protein 2;PIR121;cytoplasmic FMR1-interacting protein 2;p53-inducible protein 121
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- His
- GST
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CYFIP2 involved in several pathways and played different roles in them. We selected most pathways CYFIP2 participated on our site, such as RNA transport,Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYFIP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | KPNB1,EIF4G3,NMD3,EIF3J,EIF2B1,EIF3S10,NXF2,FXR2,PABPC1L2A,THOC5 |
| Regulation of Actin Cytoskeleton | FGF21,ENAH,ARHGEF4,SOS1,RHOAB,F2,Itgam&Itgb2,CD14,APC,ITGB3B |
Protein Function
CYFIP2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYFIP2 itself. We selected most functions CYFIP2 had, and list some proteins which have the same functions with CYFIP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NLGN3,SSR1,C3,NCF2,DAP3,Raet1c,CD80,ICAM1,NETO2,FZD3 |
Interacting Protein
CYFIP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYFIP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYFIP2.
Atp6v1a;Dlg4;Dmxl2;Abi1;Ywhab
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References
- Abekhoukh, S; Bardoni, B; et al. CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome. FRONTIERS IN CELLULAR NEUROSCIENCE 8:-(2014).
- Bozdagi, O; Sakurai, T; et al. Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice. PLOS ONE 7:-(2012).
