CTNND2
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Official Full Name
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) -
Overview
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. -
Synonyms
CTNND2;catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein);catenin delta-2;GT24;NPRAP;Catenin (cadherin associated protein) delta 2;Catenin delta 2;CTND2_HUMAN;CTNND 2;Delta catenin;Delta-catenin;GT 24;Neural plakophilin related arm repeat protein;Neural plakophilin related armadillo repeat protein;Neural plakophilin-related ARM-repeat protein;Neurojungin;OTTHUMP00000115594;OTTHUMP00000220687;OTTHUMP00000220689;OTTHUMP00000220690;T-cell delta-catenin
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CTNND2-3229H | Recombinant Human CTNND2 protein, His-tagged | E.coli | Human | His | 1043-1142 aa | |
| CTNND2-2089H | Recombinant Human CTNND2 Protein, GST-tagged | Wheat Germ | Human | GST |
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Involved Pathway
CTNND2 involved in several pathways and played different roles in them. We selected most pathways CTNND2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CTNND2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CTNND2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CTNND2 itself. We selected most functions CTNND2 had, and list some proteins which have the same functions with CTNND2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CTNND2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTNND2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTNND2.
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